SCHEMBL20850481

SCHEMBL20850481

CC(C)(C)c1ccc(-c2ccc3c(c2)c2cc(-c4ccc(C(C)(C)C)cc4)ccc2n3-c2ccc(-c3ccc(-n4c5ccc(-c6ccc(C(C)(C)C)cc6)cc5c5cc(-c6ccc(C(C)(C)C)cc6)ccc54)cc3)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ PTGES O14684 1/20 0.45
▸ KIF11 P52732 3/20 0.42
▸ NR1H4 Q96RI1 3/20 0.41
▸ KCNH2 Q12809 1/20 0.37
▸ PPARG P37231 4/20 0.37
▸ SERPINE1 P05121 3/20 0.36
▸ RXRA P19793 1/20 0.36
▸ CA12 O43570 1/20 0.36
▸ CA9 Q16790 1/20 0.36
▸ TSHR P16473 1/20 0.35
▸ PIK3CA P42336 1/20 0.35
▸ PPARA Q07869 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19735301 0.93 PTGES (0.44) PTGESKIF11NR1H4PPARGSERPINE1
SCHEMBL23485921 0.92 KDM4E (0.47) PTGESKIF11NR1H4PPARGSERPINE1
SCHEMBL11981056 0.92 KDM4E (0.47) PTGESKIF11NR1H4PPARGSERPINE1
SCHEMBL13232879 0.91 KCNH2 (0.41) PTGESKIF11NR1H4KCNH2PPARG
SCHEMBL16171587 0.90 KDM4E (0.48) PTGESKIF11NR1H4PPARGSERPINE1
SCHEMBL17228096 0.90 KDM4E (0.48) PTGESKIF11NR1H4PPARGSERPINE1
SCHEMBL20152270 0.90 KDM4E (0.48) PTGESKIF11NR1H4PPARGSERPINE1
SCHEMBL20825698 0.90 PTGES (0.44) PTGESKIF11NR1H4KCNH2PPARG
SCHEMBL24793869 0.89 KDM4E (0.49) PTGESKIF11NR1H4PPARGSERPINE1
SCHEMBL24792718 0.89 KDM4E (0.53) PTGESNR1H4PPARGSERPINE1RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11121182-B2 Organic photoelectric conversion element, optical area sensor, image pickup device, and image pickup apparatus CANON KABUSHIKI KAISHA (JP) 2021-09-14 — — US disclosed
EP-3466937-B1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR AND IMAGING DEVICE CANON KK (JP) 2021-03-24 — — EP disclosed
US-10947212-B2 Photoelectric conversion element, two-dimensional sensor, image sensor, and image pickup device CANON KABUSHIKI KAISHA (JP) 2021-03-16 — — US disclosed
US-10873032-B2 Organic photoelectric conversion element, two-dimensional sensor, image sensor, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-12-22 — — US disclosed
EP-3466937-A1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR AND IMAGING DEVICE C/o Canon Kabushiki Kaisha (JP) 2019-04-10 — — EP disclosed
US-20190092743-A1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR, AND IMAGE PICKUP DEVICE CANON KABUSHIKI KAISHA (JP) 2019-03-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190092743-A1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR, AND IMAGE PICKUP DEVICE NR2E3, CRY2, GPR3 PTGES 3234/4885KIF11 3086/4885NR1H4 1673/4885
US-10873032-B2 Organic photoelectric conversion element, two-dimensional sensor, image sensor, and imaging apparatus POU2F1, PPOX, POU2F2 PTGES 2429/4885KIF11 2662/4885NR1H4 4465/4885
US-10947212-B2 Photoelectric conversion element, two-dimensional sensor, image sensor, and image pickup device NR2E3, CRY2, GPR3 PTGES 3234/4885KIF11 3086/4885NR1H4 1673/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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