Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.64 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16522409 | 0.94 | MAOA (0.68) | MAOACHRM2MEN1KMT2ATDP1 | |
| SCHEMBL7861380 | 0.93 | MAOA (0.71) | MAOACHRM2MEN1KMT2ATDP1 | |
| SCHEMBL640522 | 0.93 | MAOA (0.71) | MAOACHRM2MEN1KMT2ATDP1 | |
| SCHEMBL372804 | 0.93 | MAOA (0.71) | MAOACHRM2MEN1KMT2ATDP1 | |
| SCHEMBL29380563 | 0.93 | MAOA (0.71) | MAOACHRM2MEN1KMT2ATDP1 | |
| SCHEMBL6900998 | 0.93 | MAOA (0.71) | MAOACHRM2MEN1KMT2ATDP1 | |
| Iodide SCHEMBL8168717 | 0.91 | MAOA (0.69) | MAOACHRM2MEN1KMT2ATDP1 | |
| Water SCHEMBL8528419 | 0.91 | MAOA (0.69) | MAOACHRM2MEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL10584193 | 0.91 | MAOA (0.69) | MAOACHRM2MEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL199811 | 0.91 | MAOA (0.69) | MAOACHRM2MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240226226-A1 | KAPPA-OPIOID RECEPTOR AGONIST IMPLANTS FOR TREATMENT OF PRURITUS | TITAN PHARMACEUTICALS INC (US) | 2024-07-11 | — | — | US | disclosed |
| US-10662177-B2 | Blocking toll-like receptor 9 signaling with small molecule antagonist | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2020-05-26 | — | — | US | disclosed |
| US-20190092758-A1 | BLOCKING TOLL-LIKE RECEPTOR 9 SIGNALING WITH SMALL MOLECULE ANTAGONIST | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2019-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190092758-A1 | BLOCKING TOLL-LIKE RECEPTOR 9 SIGNALING WITH SMALL MOLECULE ANTAGONIST | TLR9, TLR1, TLR3 | MAOA 4299/4885CHRM2 3035/4885MEN1 4468/4885 |
| US-20240226226-A1 | KAPPA-OPIOID RECEPTOR AGONIST IMPLANTS FOR TREATMENT OF PRURITUS | OPRK1, OPRL1, OPRD1 | MAOA 1059/4885CHRM2 106/4885MEN1 4855/4885 |
| US-10662177-B2 | Blocking toll-like receptor 9 signaling with small molecule antagonist | TLR9, TLR1, TLR3 | MAOA 4261/4885CHRM2 3191/4885MEN1 4489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.