Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 8/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.47 |
| ▸ | BCHE | P06276 | 4/20 | 0.47 |
| ▸ | ACHE | P22303 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10995649 | 0.82 | ALDH1A1 (0.64) | ALDH1A1LMNACHRM2GRIN1GRIN2A | |
| SCHEMBL7873203 | 0.79 | IDO1 (0.53) | ALDH1A1LMNATP53RECQL | |
| SCHEMBL15510160 | 0.79 | ALDH1A1 (0.50) | ALDH1A1LMNATP53CYP3A4TSHR | |
| SCHEMBL29386728 | 0.79 | ALDH1A1 (0.50) | ALDH1A1LMNATP53CYP3A4TSHR | |
| SCHEMBL21983038 | 0.78 | CA12 (0.68) | ALDH1A1LMNACA12CA2CYP2D6 | |
| SCHEMBL31367150 | 0.78 | CHRM2 (0.52) | ALDH1A1LMNATRPV6CHRM2GRIN1 | |
| SCHEMBL10335287 | 0.77 | ALDH1A1 (0.48) | ALDH1A1LMNARECQL | |
| SCHEMBL29676259 | 0.77 | MTNR1A (0.51) | ALDH1A1LMNATSHR | |
| SCHEMBL7645845 | 0.76 | HRH1 (0.54) | ALDH1A1LMNATP53CYP3A4TSHR | |
| SCHEMBL8387661 | 0.76 | HTR1B (0.60) | ALDH1A1CHRM2GRIN1GRIN2ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10869866-B2 | Benzathine analogs | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2020-12-22 | — | — | US | disclosed |
| US-20200113900-A1 | BENZATHINE ANALOGS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-04-16 | — | — | US | disclosed |
| US-10369150-B2 | Benzathine analogs | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2019-08-06 | — | — | US | disclosed |
| US-20190091222-A1 | BENZATHINE ANALOGS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2019-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200113900-A1 | BENZATHINE ANALOGS | HDAC10, CFTR, HBB | ALDH1A1 2621/4885LMNA 2851/4885CA12 2627/4885 |
| US-20190091222-A1 | BENZATHINE ANALOGS | HDAC10, CFTR, HBB | ALDH1A1 2621/4885LMNA 2851/4885CA12 2627/4885 |
| US-10369150-B2 | Benzathine analogs | HDAC10, CFTR, HBB | ALDH1A1 2621/4885LMNA 2851/4885CA12 2627/4885 |
| US-10869866-B2 | Benzathine analogs | HDAC10, CFTR, HBB | ALDH1A1 2621/4885LMNA 2851/4885CA12 2627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.