Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.58 |
| ▸ | CA12 | O43570 | 5/20 | 0.57 |
| ▸ | CA2 | P00918 | 5/20 | 0.57 |
| ▸ | CA9 | Q16790 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3203919 | 0.84 | MEN1 (0.47) | TYRALOX5 | |
| SCHEMBL14521268 | 0.82 | TYR (0.62) | TYRTSHRALOX5 | |
| SCHEMBL19840870 | 0.81 | CA12 (0.45) | TYRCA12CA2CA9TSHR | |
| SCHEMBL15013333 | 0.81 | CA12 (0.45) | TYRCA12CA2CA9TSHR | |
| SCHEMBL6895047 | 0.80 | TYR (0.60) | TYRTSHRALOX5 | |
| SCHEMBL17715198 | 0.78 | TYR (0.58) | TYRTSHRALOX5 | |
| SCHEMBL5458032 | 0.78 | TYR (0.58) | TYRTSHRKDM4EALOX5 | |
| SCHEMBL16994916 | 0.77 | TYR (0.47) | TYRTSHRALOX5 | |
| SCHEMBL11510302 | 0.75 | EGFR (0.72) | TYRKDM4EHSD17B10 | |
| SCHEMBL1397158 | 0.74 | TYR (1.00) | TYRTSHRALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210315895-A1 | BENZATHINE ANALOGS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2021-10-14 | — | — | US | disclosed |
| US-10369150-B2 | Benzathine analogs | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2019-08-06 | — | — | US | disclosed |
| US-20190091222-A1 | BENZATHINE ANALOGS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2019-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190091222-A1 | BENZATHINE ANALOGS | HDAC10, CFTR, HBB | TYR 1426/4885CA12 2627/4885CA2 2635/4885 |
| US-10369150-B2 | Benzathine analogs | HDAC10, CFTR, HBB | TYR 1426/4885CA12 2627/4885CA2 2635/4885 |
| US-20210315895-A1 | BENZATHINE ANALOGS | HDAC10, CFTR, HBB | TYR 1426/4885CA12 2627/4885CA2 2635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.