Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 6/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14521268 | 0.84 | TYR (0.62) | TYRALOX5MEN1MAPTKMT2A | |
| SCHEMBL5458032 | 0.80 | TYR (0.58) | TYRALOX5MEN1MAPTKMT2A | |
| SCHEMBL20852016 | 0.80 | TYR (0.58) | TYRALOX5TSHR | |
| SCHEMBL17715198 | 0.80 | TYR (0.58) | TYRALOX5MEN1MAPTKMT2A | |
| SCHEMBL11510302 | 0.77 | EGFR (0.72) | TYRMEN1MAPTKMT2AALOX15 | |
| SCHEMBL51397 | 0.75 | TYR (0.71) | TYRALOX5MEN1MAPTKMT2A | |
| SCHEMBL1397158 | 0.75 | TYR (1.00) | TYRALOX5MEN1MAPTKMT2A | |
| SCHEMBL18255098 | 0.74 | TYR (0.50) | TYR | |
| SCHEMBL647503 | 0.73 | TYR (0.68) | TYRALOX5MEN1MAPTKMT2A | |
| SCHEMBL11512440 | 0.72 | CA12 (0.61) | TYRALOX5MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110729-A1 | Primary N-hydroxylamines | NIH | 2004-06-10 | — | — | US | claimed |
| US-6455589-B1 | AN ORALLY ADMINISTRABLE EFFECTIVE UNIT SOLID DOSAGE OF A PRIMARY N-HYDROXYLAMINE OR A SALT, FREE OF NITRONE; USEFUL FOR REDUCING OXIDATIVE DAMAGE OR DELAYING SENESCENCE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-09-24 | — | — | US | claimed |
| CN-106458871-B | Nitrone compounds and their use in personal care | 陶氏环球技术有限责任公司 | 2018-12-28 | — | — | CN | disclosed |
| EP-3142752-B1 | NITRONE COMPOUNDS AND THEIR USE IN PERSONAL CARE | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-06-20 | — | — | EP | disclosed |
| US-9828335-B2 | Nitrone compounds and their use in personal care | DOW GLOBAL TECHNOLOGIES LLC (US) | 2017-11-28 | — | — | US | disclosed |
| US-9796667-B2 | Nitrone compounds and their use in personal care | DOW GLOBAL TECHNOLOGIES LLC (US) | 2017-10-24 | — | — | US | disclosed |
| US-20170253558-A1 | NITRONE COMPOUNDS AND THEIR USE IN PERSONAL CARE | DOW GLOBAL TECHNOLOGIES LLC | 2017-09-07 | — | — | US | disclosed |
| US-9730874-B2 | Nitrone compounds and their use in personal care | DOW GLOBAL TECHNOLOGIES LLC (US) | 2017-08-15 | — | — | US | disclosed |
| US-9701625-B2 | Nitrone compounds and their use in personal care | DOW GLOBAL TECHNOLOGIES LLC (US) | 2017-07-11 | — | — | US | disclosed |
| US-20170190655-A1 | NITRONE COMPOUNDS AND THEIR USE IN PERSONAL CARE | DOW GLOBAL TECHNOLOGIES LLC | 2017-07-06 | — | — | US | disclosed |
| US-20170079896-A1 | NITRONE COMPOUNDS AND THEIR USE IN PERSONAL CARE | DOW GLOBAL TECHNOLOGIES LLC | 2017-03-23 | — | — | US | disclosed |
| EP-3142752-A1 | NITRONE COMPOUNDS AND THEIR USE IN PERSONAL CARE | Dow Global Technologies Llc (US) | 2017-03-22 | — | — | EP | disclosed |
| CN-106458871-A | Nitrone compounds and their use in personal care | 陶氏环球技术有限责任公司 | 2017-02-22 | — | — | CN | disclosed |
| EP-3114110-A1 | NITRONE COMPOUNDS AND THEIR USE IN PERSONAL CARE | Dow Global Technologies LLC (US) | 2017-01-11 | — | — | EP | disclosed |
| US-20160362361-A1 | NITRONE COMPOUNDS AND THEIR USE IN PERSONAL CARE | DOW GLOBAL TECHNOLOGIES LLC | 2016-12-15 | — | — | US | disclosed |
| WO-2015175310-A1 | NITRONE COMPOUNDS AND THEIR USE IN PERSONAL CARE | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-11-19 | — | — | WO | disclosed |
| WO-2015134688-A1 | NITRONE COMPOUNDS AND THEIR USE IN PERSONAL CARE | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-09-11 | — | — | WO | disclosed |
| JP-2004315496-A | FUSED HETEROCYCLIC RING COMPOUND | TAKEDA CHEM IND LTD | 2004-11-11 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160362361-A1 | NITRONE COMPOUNDS AND THEIR USE IN PERSONAL CARE | NOX1, NOX5, NOS1 | TYR 243/4885ALOX5 791/4885MEN1 1140/4885 |
| US-20170253558-A1 | NITRONE COMPOUNDS AND THEIR USE IN PERSONAL CARE | NOX1, NOX5, NOS1 | TYR 243/4885ALOX5 791/4885MEN1 1140/4885 |
| US-20170190655-A1 | NITRONE COMPOUNDS AND THEIR USE IN PERSONAL CARE | NOX1, NOX3, NOX5 | TYR 271/4885ALOX5 874/4885MEN1 793/4885 |
| US-20170079896-A1 | NITRONE COMPOUNDS AND THEIR USE IN PERSONAL CARE | NOX1, NOX5, NOX3 | TYR 226/4885ALOX5 927/4885MEN1 901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.