Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 5/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14521268 | 0.82 | TYR (0.62) | TYRCYP3A4ALOX15KMT2AMAPT | |
| SCHEMBL6895047 | 0.80 | TYR (0.60) | TYRCYP3A4ALOX15KMT2AMAPT | |
| SCHEMBL20852016 | 0.78 | TYR (0.58) | TYRALOX5KDM4ETSHR | |
| SCHEMBL17715198 | 0.78 | TYR (0.58) | TYRCYP3A4ALOX15KMT2AMAPT | |
| SCHEMBL11510302 | 0.75 | EGFR (0.72) | TYRALOX15MAPK1KMT2AMAPT | |
| SCHEMBL633312 | 0.75 | TYR (0.65) | TYRCYP3A4ALOX15KMT2AMAPT | |
| SCHEMBL30255614 | 0.75 | TYR (0.65) | TYRCYP3A4ALOX15KMT2AMAPT | |
| SCHEMBL1397158 | 0.74 | TYR (1.00) | TYRCYP3A4ALOX15KMT2AMAPT | |
| SCHEMBL51397 | 0.74 | TYR (0.71) | TYRCYP3A4ALOX15KMT2AMAPT | |
| SCHEMBL2981070 | 0.74 | EGFR (0.59) | TYRMAPTALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070078185-A1 | Methods and compositions for controlling invertebrate pests | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2007-04-05 | — | — | US | claimed |
| WO-2006116184-A2 | METHODS AND COMPOSITIONS FOR CONTROLLING INVERTEBRATE PESTS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2006-11-02 | — | — | WO | claimed |
| US-20070078185-A1 | Methods and compositions for controlling invertebrate pests | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2007-04-05 | — | — | US | disclosed |
| US-20070078185-A1 | Methods and compositions for controlling invertebrate pests | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2007-04-05 | — | — | US | disclosed |
| US-20070078185-A1 | Methods and compositions for controlling invertebrate pests | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2007-04-05 | — | — | US | disclosed |
| WO-2006116184-A2 | METHODS AND COMPOSITIONS FOR CONTROLLING INVERTEBRATE PESTS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2006-11-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078185-A1 | Methods and compositions for controlling invertebrate pests | DDT, TYR, DDC | TYR 2/4885CYP3A4 3234/4885ALOX15 3657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.