Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | PCNA | P12004 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10305077 | 0.85 | ADORA3 (0.53) | ADORA3HSD17B10SLC7A5USP2ALOX15 | |
| SCHEMBL18401480 | 0.82 | ADORA3 (0.53) | ADORA3HSD17B10SLC7A5USP2ALOX15 | |
| SCHEMBL20852606 | 0.82 | HSD17B10 (0.53) | ADORA3HSD17B10SLC7A5USP2ALOX15 | |
| SCHEMBL20852442 | 0.78 | ITGB3 (0.64) | ADORA3HSD17B10SLC7A5USP2ALOX15 | |
| SCHEMBL29510634 | 0.75 | SLC7A5 (0.58) | ADORA3HSD17B10SLC7A5USP2ALOX15 | |
| SCHEMBL4616523 | 0.72 | HSD17B10 (0.68) | ADORA3HSD17B10SLC7A5USP2ALOX15 | |
| SCHEMBL358292 | 0.72 | HSD17B10 (0.68) | ADORA3HSD17B10SLC7A5USP2ALOX15 | |
| SCHEMBL3297372 | 0.71 | THRB (0.59) | ADORA3HSD17B10SLC7A5USP2ALOX15 | |
| SCHEMBL3297376 | 0.71 | THRB (0.59) | ADORA3HSD17B10SLC7A5USP2ALOX15 | |
| SCHEMBL21556878 | 0.71 | ITGB3 (0.67) | ADORA3HSD17B10SLC7A5USP2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3567029-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | Lantheus Medical Imaging, Inc. (US) | 2019-11-13 | — | — | EP | disclosed |
| EP-2753605-B1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING INC (US) | 2019-03-27 | — | — | EP | disclosed |