Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 10/20 | 0.59 |
| ▸ | THRA | P10827 | 7/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3297376 | 1.00 | THRB (0.59) | THRBTHRAADORA3HSD17B10SLC7A5 | |
| SCHEMBL3290593 | 0.86 | THRB (0.58) | THRBTHRAADORA3HSD17B10SLC7A5 | |
| SCHEMBL3291891 | 0.86 | THRB (0.58) | THRBTHRAADORA3HSD17B10SLC7A5 | |
| SCHEMBL18401480 | 0.80 | ADORA3 (0.53) | THRBTHRAADORA3HSD17B10SLC7A5 | |
| SCHEMBL25180570 | 0.79 | SLC7A5 (0.58) | THRBTHRAADORA3HSD17B10SLC7A5 | |
| SCHEMBL7280620 | 0.79 | THRB (0.56) | THRBTHRAADORA3HSD17B10SLC7A5 | |
| SCHEMBL29510634 | 0.79 | SLC7A5 (0.58) | THRBTHRAADORA3HSD17B10SLC7A5 | |
| SCHEMBL13957567 | 0.79 | SLC7A5 (0.58) | THRBTHRAADORA3HSD17B10SLC7A5 | |
| SCHEMBL19113817 | 0.78 | PCNA (0.74) | THRBTHRAADORA3HSD17B10SLC7A5 | |
| SCHEMBL39086 | 0.77 | SIRT5 (0.58) | THRBTHRAADORA3HSD17B10SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723068-B2 | Gene cluster involved in safracin biosynthesis and its uses for genetic engineering | PHARMAMAR, S.A. (ES) | 2010-05-25 | — | — | US | disclosed |
| EP-1576159-B9 | THE GENE CLUSTER INVOLVED IN SAFRACIN BIOSYNTHESIS AND ITS USES FOR GENETIC ENGINEERING | PHARMA MAR SA (ES) | 2009-12-16 | — | — | EP | disclosed |
| EP-1576159-B1 | THE GENE CLUSTER INVOLVED IN SAFRACIN BIOSYNTHESIS AND ITS USES FOR GENETIC ENGINEERING | PHARMA MAR SA (ES) | 2009-07-01 | — | — | EP | disclosed |