Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20855410 | 1.00 | SCN4A (0.42) | SCN4AMEN1KMT2AADRA2AADRA1A | |
| SCHEMBL20869166 | 0.83 | MEN1 (0.43) | SCN4AMEN1KMT2AADRA2AADRA1A | |
| SCHEMBL20868718 | 0.81 | LMNA (0.42) | MEN1KMT2ALMNATTRALDH1A1 | |
| SCHEMBL20855752 | 0.80 | USP2 (0.41) | MEN1KMT2AADRA2AADRA1ACYP2D6 | |
| SCHEMBL20855556 | 0.80 | KDM4E (0.43) | ADRA2AADRA1ALMNAALDH1A1HTT | |
| SCHEMBL20868996 | 0.79 | LMNA (0.55) | MEN1KMT2AADRA2AADRA1ALMNA | |
| SCHEMBL1748248 | 0.79 | LMNA (0.55) | MEN1KMT2AADRA2AADRA1ALMNA | |
| SCHEMBL30963569 | 0.77 | CA1 (0.46) | SCN4ALMNAALDH1A1HTTNPSR1 | |
| SCHEMBL84489 | 0.74 | LPAR1 (0.50) | MEN1KMT2AHTR3EHTR3BHTR3A | |
| SCHEMBL8782180 | 0.73 | ADRA2A (0.69) | MEN1KMT2AADRA2AADRA1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019063748-A1 | ROR-GAMMA INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-04-04 | — | — | WO | disclosed |