Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | SCN4A | P35499 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20855412 | 0.83 | SCN4A (0.42) | MEN1KMT2AADRA2AADRA1AHTR3E | |
| SCHEMBL20855410 | 0.83 | SCN4A (0.42) | MEN1KMT2AADRA2AADRA1AHTR3E | |
| SCHEMBL20868717 | 0.81 | ALDH1A1 (0.44) | MEN1KMT2AADRA2AADRA1ALMNA | |
| SCHEMBL1661357 | 0.81 | ADRA1A (0.63) | MEN1KMT2AADRA2AADRA1ALMNA | |
| SCHEMBL16959649 | 0.80 | MEN1 (0.43) | MEN1KMT2AADRA2AADRA1AHTR3E | |
| SCHEMBL1748248 | 0.79 | LMNA (0.55) | MEN1KMT2AADRA2AADRA1AHTR3E | |
| SCHEMBL20868996 | 0.79 | LMNA (0.55) | MEN1KMT2AADRA2AADRA1AHTR3E | |
| SCHEMBL15797722 | 0.77 | AGTR1 (0.49) | LMNAPDCD1LG2CD274ALDH1A1POLB | |
| SCHEMBL21136940 | 0.77 | MEN1 (0.45) | MEN1KMT2AADRA2AADRA1AHTR3E | |
| SCHEMBL1439383 | 0.77 | AGTR1 (0.49) | LMNAPDCD1LG2CD274ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019063748-A1 | ROR-GAMMA INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-04-04 | — | — | WO | disclosed |