Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | GCK | P35557 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30644985 | 0.99 | L3MBTL1 (0.43) | L3MBTL1SMN1; SMN2KMT2AF10CARM1 | |
| Hydrochloric Acid SCHEMBL28419688 | 0.99 | L3MBTL1 (0.43) | L3MBTL1SMN1; SMN2KMT2AF10CARM1 | |
| Hydrochloric Acid SCHEMBL28412914 | 0.88 | KMT2A (0.44) | SMN1; SMN2KMT2AF10F2PRSS1 | |
| Hydrochloric Acid SCHEMBL30644977 | 0.88 | KMT2A (0.44) | SMN1; SMN2KMT2AF10F2PRSS1 | |
| SCHEMBL31109310 | 0.87 | CARM1 (0.48) | L3MBTL1SMN1; SMN2KMT2ACARM1PRMT6 | |
| SCHEMBL20546749 | 0.87 | PTGS1 (0.52) | SMN1; SMN2KMT2AF10ALDH1A1MAPT | |
| SCHEMBL31109331 | 0.87 | PTGS1 (0.52) | SMN1; SMN2KMT2AF10ALDH1A1MAPT | |
| SCHEMBL13724830 | 0.86 | L3MBTL1 (0.55) | L3MBTL1SMN1; SMN2KMT2AALDH1A1MTNR1B | |
| Hydrochloric Acid SCHEMBL28410339 | 0.86 | SMN1; SMN2 (0.42) | SMN1; SMN2KMT2AF10CARM1PRMT6 | |
| Hydrochloric Acid SCHEMBL30644955 | 0.86 | SMN1; SMN2 (0.42) | SMN1; SMN2KMT2AF10CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190225602-A1 | Propionic Acid Derivatives and Methods of Use Thereof | AVIARA PHARMACEUTICALS, INC. (US) | 2019-07-25 | — | — | US | disclosed |
| US-10246451-B2 | Propionic acid derivatives and methods of use thereof | AVIARA PHARMACEUTICALS, INC. (US) | 2019-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10246451-B2 | Propionic acid derivatives and methods of use thereof | ITGA4, ITGB3, ITGB5 | L3MBTL1 3880/4885SMN1; SMN2 2184/4885KMT2A 4212/4885 |
| US-20190225602-A1 | Propionic Acid Derivatives and Methods of Use Thereof | ITGA4, ITGB3, ITGB4 | L3MBTL1 3328/4885SMN1; SMN2 1998/4885KMT2A 4047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.