Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 2/20 | 0.42 |
| ▸ | JAK1 | P23458 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25410856 | 0.94 | SCD5 (0.46) | STSOPRM1OPRL1SCD5GPR119 | |
| SCHEMBL16600822 | 0.91 | GRIN2B (0.50) | STSSCD5GPR119OPRD1OPRK1 | |
| SCHEMBL9937601 | 0.87 | STS (0.46) | STSGPR119OPRD1OPRK1GRIN2B | |
| SCHEMBL2993411 | 0.82 | OPRD1 (0.48) | STSSCD5GPR119OPRD1OPRK1 | |
| SCHEMBL2951728 | 0.82 | OPRD1 (0.53) | STSOPRM1OPRL1GPR119OPRD1 | |
| SCHEMBL25412681 | 0.81 | JAK2 (0.42) | STSSCD5GPR119OPRD1OPRK1 | |
| SCHEMBL25306708 | 0.80 | GPR119 (0.50) | STSSCD5GPR119OPRD1OPRK1 | |
| SCHEMBL26986851 | 0.78 | STS (0.46) | STSGPR119OPRD1OPRK1JAK2 | |
| SCHEMBL26631461 | 0.77 | SCD5 (0.48) | SCD5GPR119OPRD1OPRK1CYP11B2 | |
| SCHEMBL19173661 | 0.77 | RORC (0.53) | STSGPR119OPRD1OPRK1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3461827-A1 | SELECTIVE OCTAHYDRO-CYCLOPENTA[C]PYRROLE NEGATIVE MODULATORS OF NR2B | Cadent Therapeutics, Inc. (US) | 2019-04-03 | — | — | EP | disclosed |