Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 7/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.39 |
| ▸ | PLG | P00747 | 2/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.38 |
| ▸ | MYLK4 | Q86YV6 | 2/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.38 |
| ▸ | Q9HBH1 | 1/20 | 0.37 | |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14966039 | 0.83 | SMN1; SMN2 (0.45) | LTA4HSPHK1KLKB1PLGROCK1 | |
| SCHEMBL17637516 | 0.82 | LTA4H (0.56) | LTA4HSPHK1ROCK1MYLK4SPHK2 | |
| SCHEMBL17661962 | 0.82 | LTA4H (0.56) | LTA4HSPHK1ROCK1MYLK4SPHK2 | |
| SCHEMBL20174120 | 0.81 | LTA4H (0.50) | LTA4HKLKB1PLGPDFCA1 | |
| SCHEMBL13258710 | 0.78 | LTA4H (0.62) | LTA4HSPHK1SPHK2 | |
| SCHEMBL18738463 | 0.78 | SMN1; SMN2 (0.45) | SPHK1KLKB1PLGSPHK2PDF | |
| SCHEMBL29335395 | 0.78 | KLKB1 (0.43) | LTA4HSPHK1KLKB1PLGSPHK2 | |
| SCHEMBL24864663 | 0.75 | KLKB1 (0.48) | LTA4HSPHK1KLKB1PLGSPHK2 | |
| SCHEMBL23448620 | 0.75 | CA1 (0.45) | SPHK1SPHK2PDFCA1CA2 | |
| SCHEMBL29330014 | 0.75 | SMN1; SMN2 (0.40) | SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019065964-A1 | ANTIBODY-PYRROLOBENZODIAZEPINE DERIVATIVE CONJUGATE | 第一三共株式会社 | 2019-04-04 | — | — | WO | disclosed |