Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.48 |
| ▸ | Q9HBH1 | 1/20 | 0.48 | |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.42 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | MMP3 | P08254 | 3/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.39 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | NMT2 | O60551 | 1/20 | 0.38 |
| ▸ | NMT1 | P30419 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | CPA2 | P48052 | 1/20 | 0.38 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24864484 | 0.89 | KLKB1 (0.47) | KLKB1PDFPLGSSTR3CALCRL | |
| SCHEMBL29335395 | 0.86 | KLKB1 (0.43) | KLKB1PDFPLGSSTR3CALCRL | |
| SCHEMBL21157965 | 0.85 | FURIN (0.38) | SPHK1 | |
| SCHEMBL17067271 | 0.85 | KLKB1 (0.47) | KLKB1PDFPLGSSTR3CALCRL | |
| SCHEMBL15686242 | 0.82 | NMT2 (0.45) | KLKB1PDFPLGSSTR3CALCRL | |
| SCHEMBL24864487 | 0.82 | KLKB1 (0.44) | KLKB1PDFPLGSSTR3CALCRL | |
| SCHEMBL16645085 | 0.82 | FURIN (0.45) | KLKB1PDFPLGSSTR3CALCRL | |
| SCHEMBL14966039 | 0.81 | SMN1; SMN2 (0.45) | KLKB1PDFPLGCALCRLCA1 | |
| SCHEMBL18738463 | 0.81 | SMN1; SMN2 (0.45) | KLKB1PDFPLGCALCRLMMP3 | |
| SCHEMBL29342074 | 0.81 | KLKB1 (0.42) | KLKB1PDFPLGSSTR3CALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280227-A2 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | PROFOUNDBIO US CO. (US) | 2023-01-12 | — | — | WO | disclosed |