Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 2/20 | 0.42 |
| ▸ | GOPC | Q9HD26 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8775873 | 0.80 | TBXAS1 (0.52) | CFTRGOPCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9717892 | 0.80 | SMN1; SMN2 (0.47) | CFTRGOPCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9718025 | 0.80 | CFTR (0.42) | CFTRGOPCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20098043 | 0.79 | CFTR (0.57) | CFTRGOPCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21770565 | 0.79 | CFTR (0.47) | CFTRGOPCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23689571 | 0.79 | CFTR (0.47) | CFTRGOPCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11337414 | 0.79 | CFTR (0.47) | CFTRGOPCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL24919838 | 0.79 | CFTR (0.47) | CFTRGOPCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4636038 | 0.78 | RIPK1 (0.52) | — | |
| SCHEMBL2420685 | 0.77 | SMN1; SMN2 (0.47) | CFTRGOPCSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019067224-A1 | METHODS OF TREATING APOPTOSIS AND ALTERING PROGRAMMED CELL DEATH | MYMD PHARMACEUTICALS, INC. (US) | 2019-04-04 | — | — | WO | disclosed |