SCHEMBL4636038

SCHEMBL4636038

C=CCCC(C)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.52
TAAR1 Q96RJ0 3/20 0.48
TRPA1 O75762 4/20 0.44
AOC3 Q16853 2/20 0.44
CYP2C19 P33261 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4635937 0.88 RIPK1 (0.48) RIPK1TAAR1TRPA1AOC3CYP2C19
SCHEMBL2750250 0.86 RIPK1 (0.47) RIPK1TAAR1TRPA1AOC3CYP2C19
SCHEMBL17183735 0.85 RIPK1 (0.46) RIPK1TAAR1TRPA1AOC3CYP2C19
SCHEMBL17183771 0.85 RIPK1 (0.46) RIPK1TAAR1TRPA1AOC3CYP2C19
SCHEMBL17183818 0.85 RIPK1 (0.46) RIPK1TAAR1TRPA1AOC3CYP2C19
SCHEMBL17183737 0.85 RIPK1 (0.46) RIPK1TAAR1TRPA1AOC3CYP2C19
SCHEMBL17183640 0.85 RIPK1 (0.46) RIPK1TAAR1TRPA1AOC3CYP2C19
SCHEMBL17183799 0.85 RIPK1 (0.46) RIPK1TAAR1TRPA1AOC3CYP2C19
SCHEMBL4578844 0.81 RIPK1 (0.53) RIPK1TAAR1TRPA1AOC3
SCHEMBL8510683 0.80 HRH1 (0.50) TAAR1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5034561-A Formation of dialkyltetrahydronaphthalene in the presence of a zeolite catalyst AMOCO CORPORATION (US) 1991-07-23 US claimed
US-4994539-A Ethylene-unsaturated aromatic copolymer NIPPON PETROCHEMICALS CO., LTD. (JP) 1991-02-19 US claimed
US-12275680-B2 Method for producing 1,4-dimethyltetralin SINOCHEM HEBEI FUHENG CO., LTD (CN) 2025-04-15 US disclosed
US-12240805-B2 Method for producing 1,4-dimethylnaphthalene SINOCHEM HEBEI FUHENG CO., LTD (CN) 2025-03-04 US disclosed
US-20240228406-A1 METHOD FOR PRODUCING 1,4-DIMETHYLNAPHTHALENE SINOCHEM HEBEI FUHENG CO., LTD. (CN) 2024-07-11 US disclosed
US-20240228408-A1 METHOD FOR PRODUCING 1,4-DIMETHYLTETRALIN SINOCHEM HEBEI FUHENG CO., LTD. (CN) 2024-07-11 US disclosed
EP-4148034-A1 METHOD FOR MANUFACTURING 1,4-DIMETHYLNAPHTHALENE Sinochem Hebei Fuheng Co., Ltd (CN) 2023-03-15 EP disclosed
CN-115504849-A Method for producing 1,4-dimethyltetralin 河北中化滏恒股份有限公司 2022-12-23 CN disclosed
WO-2022257260-A1 METHOD FOR MANUFACTURING 1,4-DIMETHYLNAPHTHALENE 河北中化滏恒股份有限公司 2022-12-15 WO disclosed
WO-2022257261-A1 METHOD FOR PREPARING 1,4-DIMETHYLTETRALIN 河北中化滏恒股份有限公司 2022-12-15 WO disclosed
US-11492432-B2 Resin for nanoimprinting, laminate containing resin for nanoimprinting, printed board containing resin for nanoimprinting, and method for producing nanoimprint substrate JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2022-11-08 US disclosed
EP-0547336-A1 Process for producing alkenylbenzene TEIJIN LIMITED (JP) 1993-06-23 EP disclosed
US-5198594-A Alkylation of alkylaromatics promoted by sonicated alkali metal AMOCO CORPORATION (US) 1993-03-30 US disclosed
EP-0461913-A2 Catalytic alkenylbenzene cyclization AMOCO CORPORATION (US) 1991-12-18 EP disclosed
US-5034561-A Formation of dialkyltetrahydronaphthalene in the presence of a zeolite catalyst AMOCO CORPORATION (US) 1991-07-23 US disclosed
US-4740647-A COPPER ALUMINUM BORATE TO CATALYZE DEHYDROCYCLIZATION OF ALKENYL AROMATIC COMPOUND AMOCO CORPORATION (US) 1988-04-26 US disclosed
US-4112024-A PESTICIDES EXXON RESEARCH & ENGINEERING CO. (US) 1978-09-05 US disclosed
US-4003939-A PESTICIDES EXXON RESEARCH AND ENGINEERING COMPANY (US) 1977-01-18 US disclosed
US-3997616-A FROM ALKENYLBENZENE, CYCLIZATION CATALYST TEIJIN LIMITED (JA) 1976-12-14 US disclosed
US-3946081-A OXIDATION CATALYSTS, GROUP V, VI, OR VII OXIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240228406-A1 METHOD FOR PRODUCING 1,4-DIMETHYLNAPHTHALENE DHPS, DNPH1, DDAH1 RIPK1 2240/4885TAAR1 3010/4885TRPA1 930/4885
US-12240805-B2 Method for producing 1,4-dimethylnaphthalene DHPS, DNPH1, DDAH1 RIPK1 2240/4885TAAR1 3010/4885TRPA1 930/4885
US-12275680-B2 Method for producing 1,4-dimethyltetralin DPYD, DHFR, MTHFD2 RIPK1 2220/4885TAAR1 467/4885TRPA1 498/4885
US-20240228408-A1 METHOD FOR PRODUCING 1,4-DIMETHYLTETRALIN DPYD, DHFR, PAH RIPK1 1967/4885TAAR1 384/4885TRPA1 668/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.