SCHEMBL20865041

SCHEMBL20865041

CC(Cc1ncc[nH]1)c1ccc(O)cc1O

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ TAAR1 Q96RJ0 8/20 0.41
▸ TYR P14679 1/20 0.39
▸ PTGER3 P43115 1/20 0.34
▸ HTR1A P08908 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29783451 1.00 TAAR1 (0.41) TAAR1TYRPTGER3HTR1A
SCHEMBL29783449 0.73 MAPT (0.55) —
SCHEMBL20865069 0.73 MAPT (0.55) —
SCHEMBL8958030 0.72 TAAR1 (0.51) TAAR1HTR1A
SCHEMBL10439615 0.72 ESR1 (0.58) TAAR1TYR
SCHEMBL9686332 0.72 TYR (0.51) TYR
SCHEMBL20865071 0.71 TYR (0.39) TYR
SCHEMBL29783452 0.71 TYR (0.39) TYR
SCHEMBL20865068 0.71 FDPS (0.41) TYR
SCHEMBL4289027 0.70 TYR (0.46) TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11389385-B2 Resorcinol derivatives for their cosmetic use L'OREAL (FR) 2022-07-19 — — US claimed
EP-3687979-B1 RESORCINOL DERIVATIVES FOR THEIR COSMETIC USE OREAL (FR) 2021-08-18 — — EP claimed
US-20200246240-A1 RESORCINOL DERIVATIVES FOR THEIR COSMETIC USE L'OREAL (FR) 2020-08-06 — — US claimed
US-11389385-B2 Resorcinol derivatives for their cosmetic use L'OREAL (FR) 2022-07-19 — — US disclosed
EP-3687979-B1 RESORCINOL DERIVATIVES FOR THEIR COSMETIC USE OREAL (FR) 2021-08-18 — — EP disclosed
EP-3687979-B1 RESORCINOL DERIVATIVES FOR THEIR COSMETIC USE OREAL (FR) 2021-08-18 — — EP disclosed
US-20200246240-A1 RESORCINOL DERIVATIVES FOR THEIR COSMETIC USE L'OREAL (FR) 2020-08-06 — — US disclosed
US-20200246240-A1 RESORCINOL DERIVATIVES FOR THEIR COSMETIC USE L'OREAL (FR) 2020-08-06 — — US disclosed
WO-2019063710-A1 RESORCINOL DERIVATIVES FOR THEIR COSMETIC USE L'OREAL (FR) 2019-04-04 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11389385-B2 Resorcinol derivatives for their cosmetic use KRT18, RBP4, RARA TAAR1 3976/4885TYR 16/4885PTGER3 2362/4885
US-20200246240-A1 RESORCINOL DERIVATIVES FOR THEIR COSMETIC USE KRT18, RARA, RBP4 TAAR1 3881/4885TYR 16/4885PTGER3 2599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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