SCHEMBL20865074

SCHEMBL20865074

CC(CC(=O)O)c1ccc(OCc2ccccc2)cc1OCc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ PTGER1 P34995 1/20 0.55
▸ PTGER4 P35408 1/20 0.55
▸ PTGER3 P43115 1/20 0.55
▸ PTGER2 P43116 1/20 0.55
▸ KMT2A Q03164 1/20 0.51
▸ SMN1; SMN2 Q16637 1/20 0.51
▸ FFAR1 O14842 6/20 0.49
▸ MMP12 P39900 1/20 0.49
▸ MAOB P27338 4/20 0.49
▸ LTA4H P09960 2/20 0.46
▸ LMNA P02545 1/20 0.46
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ FFAR4 Q5NUL3 1/20 0.46
▸ NR4A2 P43354 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20865036 0.88 LMNA (0.54) PTGER1PTGER4PTGER3PTGER2KMT2A
SCHEMBL21982036 0.87 FFAR1 (0.50) FFAR1MAOBLTA4HFFAR4
SCHEMBL18986242 0.86 MAOB (0.50) PTGER1PTGER4PTGER3PTGER2MAOB
SCHEMBL18986249 0.85 LMNA (0.48) KMT2ASMN1; SMN2MAOBLTA4HLMNA
SCHEMBL18986192 0.85 GPR132 (0.44) SMN1; SMN2MAOBLTA4H
SCHEMBL18986214 0.85 GPR132 (0.44) SMN1; SMN2MAOBLTA4H
SCHEMBL18986273 0.85 GPR132 (0.44) SMN1; SMN2MAOBLTA4H
SCHEMBL18986264 0.83 RECQL (0.50) SMN1; SMN2LTA4HLMNAL3MBTL1
SCHEMBL18986285 0.83 GPR132 (0.55) KMT2A
SCHEMBL18986286 0.83 GPR132 (0.55) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3687979-B1 RESORCINOL DERIVATIVES FOR THEIR COSMETIC USE OREAL (FR) 2021-08-18 — — EP disclosed
US-20200246240-A1 RESORCINOL DERIVATIVES FOR THEIR COSMETIC USE L'OREAL (FR) 2020-08-06 — — US disclosed
WO-2019063710-A1 RESORCINOL DERIVATIVES FOR THEIR COSMETIC USE L'OREAL (FR) 2019-04-04 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200246240-A1 RESORCINOL DERIVATIVES FOR THEIR COSMETIC USE KRT18, RARA, RBP4 PTGER1 3241/4885PTGER4 1486/4885PTGER3 2599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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