Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | WRN | Q14191 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11249412 | 0.79 | NAAA (0.34) | NAAAALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL20865657 | 0.79 | ALDH1A1 (0.46) | ALDH1A1CYP1A2LMNAHSD17B10GAA | |
| SCHEMBL27787073 | 0.79 | NAAA (0.40) | NAAAALDH1A1CYP1A2HPGDCYP2C19 | |
| Hydrochloric Acid SCHEMBL3507298 | 0.77 | NAAA (0.39) | NAAAALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL9001040 | 0.76 | NAAA (0.41) | NAAAALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL10777615 | 0.76 | NAAA (0.38) | NAAAALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL1326486 | 0.75 | NAAA (0.44) | NAAAALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL13771559 | 0.74 | LMNA (0.42) | NAAAALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL6789266 | 0.74 | NAAA (0.40) | NAAAALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL27872544 | 0.74 | LMNA (0.38) | NAAAALDH1A1CYP1A2HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019065791-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 | 2019-04-04 | — | — | WO | disclosed |