Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28232410 | 0.89 | ALDH1A1 (0.41) | ALDH1A1LMNAHSD17B10TSHRCHRM5 | |
| SCHEMBL4688117 | 0.87 | ALDH1A1 (0.46) | ALDH1A1LMNAHSD17B10TSHRCHRM5 | |
| Hydrochloric Acid SCHEMBL4955070 | 0.85 | ALDH1A1 (0.43) | ALDH1A1LMNAHSD17B10TSHRCHRM5 | |
| SCHEMBL12191370 | 0.81 | LMNA (0.41) | ALDH1A1LMNAHSD17B10TSHRCHRM5 | |
| SCHEMBL1762048 | 0.81 | LMNA (0.41) | ALDH1A1LMNAHSD17B10TSHRCHRM5 | |
| SCHEMBL20865579 | 0.80 | ALDH1A1 (0.33) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL20865631 | 0.79 | NAAA (0.39) | ALDH1A1LMNAHSD17B10ALOX15GAA | |
| SCHEMBL9778987 | 0.79 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10TSHRCHRM5 | |
| SCHEMBL34122 | 0.79 | THRB (0.46) | ALDH1A1LMNAHSD17B10TSHRTHRB | |
| Ammonia Solution, Strong SCHEMBL27932500 | 0.77 | THRB (0.44) | ALDH1A1TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019065791-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 | 2019-04-04 | — | — | WO | disclosed |