SCHEMBL20873137

SCHEMBL20873137

O=C(O)[C@H](CO)NCC(O)COCCC[Si](O)(O)O

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.33
TGFBR1 P36897 1/20 0.30
PLA2G2C Q5R387 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20873139 0.88 SLC22A6 (0.32)
SCHEMBL20873135 0.85 FOLH1 (0.36) PLA2G2CCYP1A2CYP3A4CYP2C19
SCHEMBL20873131 0.83 TLR2 (0.40)
SCHEMBL20873145 0.82 ADRB2 (0.34) CYP1A2CYP3A4CYP2C19
SCHEMBL9515451 0.81 USP2 (0.58) USP2PLA2G2CCYP1A2CYP3A4CYP2C19
SCHEMBL28591975 0.80 C3AR1 (0.36) CYP1A2CYP3A4CYP2C19
SCHEMBL20873138 0.80 C3AR1 (0.36) CYP1A2CYP3A4CYP2C19
SCHEMBL20873149 0.80 USP2 (0.33) USP2TGFBR1
Hydrochloric Acid SCHEMBL9129314 0.80 USP2 (0.56) USP2PLA2G2CCYP1A2CYP3A4CYP2C19
SCHEMBL23988564 0.79 CYP2C19 (0.34) USP2CYP1A2CYP3A4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3466405-B1 MICROCAPSULES AND COSMETIC COMPRISING THEM SEIWA KASEI CO LTD (JP) 2023-06-28 EP disclosed
CN-109310618-B Cosmetic base material and cosmetic containing the same 株式会社成和化成 2021-07-30 CN disclosed
US-20200230034-A1 A COSMETIC SUBSTRATE AND A COSMETIC CONTAINING THE COSMETIC SUBSTRATE SEIWA KASEI COMPANY, LIMITED (JP) 2020-07-23 US disclosed
EP-3466405-A1 COSMETIC BASE AND COSMETIC COMPRISING SAME Seiwa Kasei Company, Limited (JP) 2019-04-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200230034-A1 A COSMETIC SUBSTRATE AND A COSMETIC CONTAINING THE COSMETIC SUBSTRATE SMS, CUTA, SRM USP2 2351/4885TGFBR1 3372/4885PLA2G2C 1292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.