SCHEMBL20873151

SCHEMBL20873151

O=C(O)CNCC(O)COCCC[Si](O)(O)O

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
CYP1A2 P05177 2/20 0.34
ADRB2 P07550 1/20 0.34
ADRB1 P08588 1/20 0.34
ADRB3 P13945 1/20 0.34
CYP3A4 P08684 1/20 0.32
CYP2C19 P33261 1/20 0.32
DPP4 P27487 1/20 0.31
PLA2G2C Q5R387 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23988528 0.88 ADRB2 (0.35) KDM4ECYP1A2ADRB2ADRB1ADRB3
SCHEMBL23988564 0.83 CYP2C19 (0.34) KDM4ECYP1A2CYP3A4CYP2C19
SCHEMBL15218995 0.82 KDM4E (0.41) KDM4EADRB2ADRB1ADRB3
SCHEMBL15218991 0.81 KDM4E (0.40) KDM4EADRB2
SCHEMBL19660807 0.81 KDM4E (0.40) KDM4EADRB2ADRB1ADRB3
SCHEMBL15218975 0.80 KDM4E (0.39) KDM4EADRB2
SCHEMBL9928007 0.78 KDM4E (0.42) KDM4ECYP1A2ADRB2ADRB1CYP3A4
SCHEMBL9927953 0.78 KDM4E (0.38) KDM4ECYP1A2ADRB2CYP3A4CYP2C19
SCHEMBL20873135 0.78 FOLH1 (0.36) CYP1A2CYP3A4CYP2C19PLA2G2C
SCHEMBL23988533 0.78 LPAR5 (0.36) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3466405-B1 MICROCAPSULES AND COSMETIC COMPRISING THEM SEIWA KASEI CO LTD (JP) 2023-06-28 EP disclosed
US-20210340404-A1 SILANOL COMPOSITIONS AND METHODS OF USE 3M INNOVATIVE PROPERTIES COMPANY 2021-11-04 US disclosed
CN-109310618-B Cosmetic base material and cosmetic containing the same 株式会社成和化成 2021-07-30 CN disclosed
US-20200230034-A1 A COSMETIC SUBSTRATE AND A COSMETIC CONTAINING THE COSMETIC SUBSTRATE SEIWA KASEI COMPANY, LIMITED (JP) 2020-07-23 US disclosed
EP-3466405-A1 COSMETIC BASE AND COSMETIC COMPRISING SAME Seiwa Kasei Company, Limited (JP) 2019-04-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200230034-A1 A COSMETIC SUBSTRATE AND A COSMETIC CONTAINING THE COSMETIC SUBSTRATE SMS, CUTA, SRM KDM4E 2318/4885CYP1A2 2851/4885ADRB2 2186/4885
US-20210340404-A1 SILANOL COMPOSITIONS AND METHODS OF USE EPCAM, ITGA8, CD99 KDM4E 985/4885CYP1A2 1429/4885ADRB2 3522/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.