SCHEMBL20876175

SCHEMBL20876175

CN(C(=O)Cc1ccc(-c2cc(F)ccc2F)cc1)c1nc(CO)c(S(C)(=N)=O)s1

nearest known ligand 0.70

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA12 O43570 18/20 0.70
CA1 P00915 18/20 0.70
CA2 P00918 18/20 0.70
CA5A P35218 18/20 0.70
CA9 Q16790 18/20 0.70
CA5B Q9Y2D0 18/20 0.70
WNT3A P56704 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25854831 1.00 CA12 (0.70) CA12CA1CA2CA5ACA9
SCHEMBL31213330 1.00 CA12 (0.70) CA12CA1CA2CA5ACA9
SCHEMBL22427644 1.00 CA12 (0.70) CA12CA1CA2CA5ACA9
SCHEMBL31213329 0.90 CA12 (0.83) CA12CA1CA2CA5ACA9
SCHEMBL22405737 0.90 CA12 (0.83) CA12CA1CA2CA5ACA9
SCHEMBL20876180 0.90 CA12 (0.83) CA12CA1CA2CA5ACA9
SCHEMBL20876182 0.90 CA12 (0.83) CA12CA1CA2CA5ACA9
SCHEMBL29635247 0.88 CA12 (0.73) CA12CA1CA2CA5ACA9
SCHEMBL31388226 0.88 CA12 (0.73) CA12CA1CA2CA5ACA9
SCHEMBL29635266 0.84 CA12 (0.73) CA12CA1CA2CA5ACA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137669-A1 NOVEL ENANTIOMERS OF A SERIES OF ANTIVIRAL COMPOUNDS INNOVATIVE MOLECULES GMBH (DE) 2026-05-21 US disclosed
US-12527778-B2 Enantiomers of a series of antiviral compounds INNOVATIVE MOLECULES GMBH (DE) 2026-01-20 US disclosed
US-12295945-B2 Enantiomers of substituted thiazoles as antiviral compounds INNOVATIVE MOLECULES GMBH (DE) 2025-05-13 US disclosed
US-20240316021-A1 NOVEL ENANTIOMERS OF A SERIES OF ANTIVIRAL COMPOUNDS INNOVATIVE MOLECULES GMBH (DE) 2024-09-26 US disclosed
EP-4209491-A1 ENANTIOMERS OF SUBSTITUTED THIAZOLES AS ANTIVIRAL COMPOUNDS Innovative Molecules GmbH (DE) 2023-07-12 EP disclosed
EP-4209491-A1 ENANTIOMERS OF SUBSTITUTED THIAZOLES AS ANTIVIRAL COMPOUNDS Innovative Molecules GmbH (DE) 2023-07-12 EP disclosed
EP-3692039-B1 ENANTIOMERS OF SUBSTITUTED THIAZOLES AS ANTIVIRAL COMPOUNDS INNOVATIVE MOLECULES GMBH (DE) 2022-12-14 EP disclosed
EP-3692039-B1 ENANTIOMERS OF SUBSTITUTED THIAZOLES AS ANTIVIRAL COMPOUNDS INNOVATIVE MOLECULES GMBH (DE) 2022-12-14 EP disclosed
US-20220152008-A1 Enantiomers Of Substituted Thiazoles As Antiviral Compounds INNOVATIVE MOLECULES GMBH (DE) 2022-05-19 US disclosed
US-20220152008-A1 Enantiomers Of Substituted Thiazoles As Antiviral Compounds INNOVATIVE MOLECULES GMBH (DE) 2022-05-19 US disclosed
US-11278534-B2 Enantiomers of substituted thiazoles as antiviral compounds Innovative Molecules GmbG (DE) 2022-03-22 US disclosed
US-20200289486-A1 Enantiomers Of Substituted Thiazoles As Antiviral Compounds INNOVATIVE MOLECULES GMBH (DE) 2020-09-17 US disclosed
US-20200289486-A1 Enantiomers Of Substituted Thiazoles As Antiviral Compounds INNOVATIVE MOLECULES GMBH (DE) 2020-09-17 US disclosed
EP-3692039-A1 ENANTIOMERS OF SUBSTITUTED THIAZOLES AS ANTIVIRAL COMPOUNDS Innovative Molecules GmbH (DE) 2020-08-12 EP disclosed
WO-2019068817-A1 ENANTIOMERS OF SUBSTITUTED THIAZOLES AS ANTIVIRAL COMPOUNDS INNOVATIVE MOLECULES GMBH (DE) 2019-04-11 WO disclosed
WO-2019068817-A1 ENANTIOMERS OF SUBSTITUTED THIAZOLES AS ANTIVIRAL COMPOUNDS INNOVATIVE MOLECULES GMBH (DE) 2019-04-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12295945-B2 Enantiomers of substituted thiazoles as antiviral compounds EIF2AK2, MAVS, ZC3HAV1 CA12 4867/4885CA1 4865/4885CA2 4604/4885
US-20240316021-A1 NOVEL ENANTIOMERS OF A SERIES OF ANTIVIRAL COMPOUNDS EIF2AK2, MAVS, SARS1 CA12 4748/4885CA1 4827/4885CA2 4611/4885
US-11278534-B2 Enantiomers of substituted thiazoles as antiviral compounds EIF2AK2, MAVS, ZC3HAV1 CA12 4855/4885CA1 4850/4885CA2 4269/4885
US-20220152008-A1 Enantiomers Of Substituted Thiazoles As Antiviral Compounds EIF2AK2, MAVS, ZC3HAV1 CA12 4855/4885CA1 4850/4885CA2 4269/4885
US-20200289486-A1 Enantiomers Of Substituted Thiazoles As Antiviral Compounds EIF2AK2, MAVS, ZC3HAV1 CA12 4855/4885CA1 4850/4885CA2 4269/4885
US-12527778-B2 Enantiomers of a series of antiviral compounds CA2, CA6, HCFC1 CA12 4/4885CA1 6/4885CA2 1/4885
US-20260137669-A1 NOVEL ENANTIOMERS OF A SERIES OF ANTIVIRAL COMPOUNDS IFNAR1, CCR10, EIF2AK2 CA12 2877/4885CA1 4619/4885CA2 3814/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.