Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8655542 | 0.90 | SLC6A4 (0.54) | SLC6A2SLC6A4SLC6A3AKR1C1HDAC4 | |
| SCHEMBL9790835 | 0.86 | OPRM1 (0.52) | CYP2D6SLC6A2SLC6A4SLC6A3OPRM1 | |
| SCHEMBL6485244 | 0.86 | ALDH1A1 (0.40) | CYP2D6SLC6A2SLC6A4SLC6A3OPRM1 | |
| SCHEMBL9378568 | 0.85 | OPRM1 (0.49) | CYP2D6SLC6A4OPRM1OPRL1OPRK1 | |
| SCHEMBL4576233 | 0.81 | CYP2D6 (0.45) | CYP2D6SLC6A2SLC6A4SLC6A3OPRM1 | |
| SCHEMBL25306257 | 0.81 | HTR2A (0.38) | CYP2D6SLC6A2SLC6A4SLC6A3OPRM1 | |
| SCHEMBL3380376 | 0.81 | ALDH1A1 (0.38) | CYP2D6SLC6A2SLC6A4SLC6A3OPRM1 | |
| SCHEMBL20558236 | 0.78 | CYP19A1 (0.33) | CYP2D6SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL7705762 | 0.78 | SLC6A4 (0.55) | SLC6A2SLC6A4SLC6A3OPRK1ALDH1A1 | |
| SCHEMBL19647190 | 0.77 | SLC6A2 (0.51) | CYP2D6SLC6A2SLC6A4SLC6A3OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3692019-B1 | FUNGICIDAL PICOLINAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2022-11-16 | — | — | EP | disclosed |
| US-11395489-B2 | Microbiocidal picolinamide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2022-07-26 | — | — | US | disclosed |
| US-20200267977-A1 | MICROBIOCIDAL PICOLINAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-27 | — | — | US | disclosed |
| EP-3692019-A1 | MICROBIOCIDAL PICOLINAMIDE DERIVATIVES | Syngenta Participations AG (CH) | 2020-08-12 | — | — | EP | disclosed |
| CN-111183133-A | Microbicidal picolinamide derivatives | 先正达参股股份有限公司 | 2020-05-19 | — | — | CN | disclosed |
| WO-2019068812-A1 | MICROBIOCIDAL PICOLINAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-04-11 | — | — | WO | disclosed |
| US-20160126471-A1 | ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE | SAMSUNG SDI CO., LTD. (KR) | 2016-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11395489-B2 | Microbiocidal picolinamide derivatives | PRF1, CASP1, FPR1 | CYP2D6 417/4885SLC6A2 3920/4885SLC6A4 3476/4885 |
| US-20200267977-A1 | MICROBIOCIDAL PICOLINAMIDE DERIVATIVES | PRF1, CASP1, FPR1 | CYP2D6 417/4885SLC6A2 3920/4885SLC6A4 3476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.