Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 4/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | DRD3 | P35462 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20877110 | 0.86 | ALDH1A1 (0.47) | SLC6A2SLC6A4PRMT5WDR77DRD4 | |
| SCHEMBL20877035 | 0.81 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL20877016 | 0.80 | POLB (0.40) | SLC6A2SLC6A4POLBPRMT5WDR77 | |
| SCHEMBL4897711 | 0.75 | MEN1 (0.64) | PRMT5WDR77MEN1KMT2AADRB3 | |
| SCHEMBL4897725 | 0.75 | MEN1 (0.64) | PRMT5WDR77MEN1KMT2AADRB3 | |
| SCHEMBL12122796 | 0.73 | SLC6A2 (0.47) | SLC6A2SLC6A4POLBSLC6A3MEN1 | |
| SCHEMBL7825517 | 0.73 | PRMT5 (0.40) | SLC6A2SLC6A4PRMT5WDR77L3MBTL1 | |
| SCHEMBL267463 | 0.71 | LMNA (0.68) | POLBL3MBTL1KDM4EMEN1KMT2A | |
| SCHEMBL258823 | 0.71 | HIF1A (0.75) | POLBADRB3CYP2D6HIF1A | |
| SCHEMBL10569173 | 0.70 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3692018-A1 | MODULATORS OF CELL ADHESION, METHODS AND COMPOSITIONS THEREFOR | Blaschuk, Orest (US) | 2020-08-12 | — | — | EP | disclosed |
| WO-2019070816-A1 | MODULATORS OF CELL ADHESION, METHODS AND COMPOSITIONS THEREFOR | Zonula Incorporated (CA) | 2019-04-11 | — | — | WO | disclosed |