Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20877111 | 0.89 | ALDH1A1 (0.42) | SLC6A2SLC6A4KCNH2MEN1KMT2A | |
| SCHEMBL20877121 | 0.82 | HTR2A (0.38) | SLC6A2SLC6A4ABCB1MEN1KMT2A | |
| SCHEMBL20877037 | 0.82 | HTR2A (0.38) | SLC6A2SLC6A4ABCB1MEN1KMT2A | |
| SCHEMBL20877598 | 0.82 | SLC6A4 (0.41) | SLC6A2SLC6A4KCNH2 | |
| SCHEMBL20877014 | 0.80 | SLC6A2 (0.47) | POLBCYP2D6ADRB3SLC6A2SLC6A4 | |
| SCHEMBL20877110 | 0.68 | ALDH1A1 (0.47) | SLC6A2SLC6A4KCNH2MEN1KMT2A | |
| SCHEMBL4897711 | 0.67 | MEN1 (0.64) | CYP2D6ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL4897725 | 0.67 | MEN1 (0.64) | CYP2D6ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL258823 | 0.66 | HIF1A (0.75) | POLBCYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL10569173 | 0.66 | SLC6A2 (0.43) | CYP2D6LMNASLC6A2SLC6A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3692018-A1 | MODULATORS OF CELL ADHESION, METHODS AND COMPOSITIONS THEREFOR | Blaschuk, Orest (US) | 2020-08-12 | — | — | EP | disclosed |
| WO-2019070816-A1 | MODULATORS OF CELL ADHESION, METHODS AND COMPOSITIONS THEREFOR | Zonula Incorporated (CA) | 2019-04-11 | — | — | WO | disclosed |