Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20877037 | 1.00 | HTR2A (0.38) | HTR2ASLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL20877598 | 0.86 | SLC6A4 (0.41) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20877111 | 0.85 | ALDH1A1 (0.42) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL20877016 | 0.82 | POLB (0.40) | SLC6A2SLC6A4MEN1KMT2AABCB1 | |
| SCHEMBL20877035 | 0.82 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL20877542 | 0.71 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20877110 | 0.67 | ALDH1A1 (0.47) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL7823918 | 0.66 | LSS (0.48) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6667990 | 0.65 | ADRB3 (0.50) | — | |
| SCHEMBL28001069 | 0.65 | LMNA (0.53) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3692018-A1 | MODULATORS OF CELL ADHESION, METHODS AND COMPOSITIONS THEREFOR | Blaschuk, Orest (US) | 2020-08-12 | — | — | EP | claimed |
| WO-2019070816-A1 | MODULATORS OF CELL ADHESION, METHODS AND COMPOSITIONS THEREFOR | Zonula Incorporated (CA) | 2019-04-11 | — | — | WO | claimed |