Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19849360 | 1.00 | SIGMAR1 (0.34) | SIGMAR1CTSBCTSSCTSKLMNA | |
| SCHEMBL24098244 | 0.85 | KMT2A (0.35) | SIGMAR1CTSBCTSSCTSKLMNA | |
| SCHEMBL14981005 | 0.82 | CTSB (0.33) | CTSBCTSSCTSKEPHX1 | |
| SCHEMBL14708929 | 0.82 | CTSB (0.33) | CTSBCTSSCTSKEPHX1 | |
| SCHEMBL12799762 | 0.81 | SIGMAR1 (0.34) | SIGMAR1CTSBCTSSCTSKLMNA | |
| SCHEMBL24098242 | 0.79 | CTSB (0.35) | SIGMAR1CTSBCTSSCTSKLMNA | |
| SCHEMBL20879992 | 0.79 | CYP1A2 (0.37) | SIGMAR1 | |
| SCHEMBL12900874 | 0.79 | CYP1A2 (0.37) | SIGMAR1 | |
| SCHEMBL23020579 | 0.78 | KMT2A (0.37) | SIGMAR1CTSBCTSSCTSKLMNA | |
| SCHEMBL12900866 | 0.78 | KMT2A (0.37) | SIGMAR1CTSBCTSSCTSKLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3782649-A1 | BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS | Ascendis Pharma A/S (DK) | 2021-02-24 | — | — | EP | disclosed |
| EP-2459220-B1 | BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS | ASCENDIS PHARMA AS (DK) | 2020-09-09 | — | — | EP | disclosed |
| EP-2237799-B1 | PRODRUG COMPRISING A SELF-CLEAVABLE LINKER | ASCENDIS PHARMA AS (DK) | 2019-04-10 | — | — | EP | disclosed |