Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | DRD1 | P21728 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12900866 | 0.91 | KMT2A (0.37) | KMT2ACHRM2CHRM1CYP3A4CHRM4 | |
| SCHEMBL23020579 | 0.91 | KMT2A (0.37) | KMT2ACHRM2CHRM1CYP3A4CHRM4 | |
| SCHEMBL20879974 | 0.85 | SIGMAR1 (0.34) | LMNASIGMAR1CTSBCTSSCTSK | |
| SCHEMBL19849360 | 0.85 | SIGMAR1 (0.34) | LMNASIGMAR1CTSBCTSSCTSK | |
| SCHEMBL14981005 | 0.80 | CTSB (0.33) | CTSBCTSSCTSK | |
| SCHEMBL14708929 | 0.80 | CTSB (0.33) | CTSBCTSSCTSK | |
| SCHEMBL12900874 | 0.76 | CYP1A2 (0.37) | CYP3A4CYP1A2CYP2D6TSHRSIGMAR1 | |
| SCHEMBL20879992 | 0.76 | CYP1A2 (0.37) | CYP3A4CYP1A2CYP2D6TSHRSIGMAR1 | |
| SCHEMBL9887647 | 0.73 | L3MBTL1 (0.34) | CHRM2CHRM1CHRM4CHRM3LMNA | |
| SCHEMBL14980975 | 0.73 | L3MBTL1 (0.34) | CHRM2CHRM1CHRM4CHRM3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3922267-A1 | PEGYLATED RECOMBINANT HUMAN GROWTH HORMONE COMPOUNDS | ASCENDIS PHARMA ENDOCRINOLOGY DIVISION A/S (DK) | 2021-12-15 | — | — | EP | disclosed |