Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | PEPD | P12955 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14981005 | 1.00 | CTSB (0.33) | CTSBCTSSCTSKEPHX1PEPD | |
| SCHEMBL23020579 | 0.82 | KMT2A (0.37) | CTSBCTSSCTSKEPHX1 | |
| SCHEMBL12900866 | 0.82 | KMT2A (0.37) | CTSBCTSSCTSKEPHX1 | |
| SCHEMBL20879974 | 0.82 | SIGMAR1 (0.34) | CTSBCTSSCTSKEPHX1 | |
| SCHEMBL19849360 | 0.82 | SIGMAR1 (0.34) | CTSBCTSSCTSKEPHX1 | |
| SCHEMBL14980975 | 0.80 | L3MBTL1 (0.34) | — | |
| SCHEMBL9887646 | 0.80 | L3MBTL1 (0.34) | — | |
| SCHEMBL24098244 | 0.80 | KMT2A (0.35) | CTSBCTSSCTSK | |
| SCHEMBL9887647 | 0.80 | L3MBTL1 (0.34) | — | |
| SCHEMBL23020573 | 0.79 | L3MBTL1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013024049-A1 | PROTEIN CARRIER-LINKED PRODRUGS | ASCENDIS PHARMA A/S (DK) | 2013-02-21 | — | — | WO | disclosed |