Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.69 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.69 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.69 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | CDC42 | P60953 | 1/20 | 0.69 |
| ▸ | RAC1 | P63000 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14817408 | 1.00 | PTGS2 (0.69) | PTGS2AKR1C3AKR1C2PTGS1TSHR | |
| SCHEMBL22217506 | 1.00 | PTGS2 (0.69) | PTGS2AKR1C3AKR1C2PTGS1TSHR | |
| SCHEMBL13340952 | 0.88 | PTGS2 (0.66) | PTGS2AKR1C3AKR1C2PTGS1TSHR | |
| SCHEMBL22651687 | 0.85 | NPSR1 (0.56) | PTGS2AKR1C3AKR1C2PTGS1TSHR | |
| SCHEMBL12327361 | 0.84 | PTGS2 (0.61) | PTGS2AKR1C3AKR1C2PTGS1TSHR | |
| SCHEMBL5534049 | 0.82 | PTGS2 (0.81) | PTGS2AKR1C3AKR1C2PTGS1TSHR | |
| Naproxen SCHEMBL42434 | 0.82 | AKR1C3 (1.00) | PTGS2AKR1C3AKR1C2PTGS1TSHR | |
| SCHEMBL20887114 | 0.82 | PTGS2 (0.81) | PTGS2AKR1C3AKR1C2PTGS1TSHR | |
| Naproxen SCHEMBL616149 | 0.82 | AKR1C3 (1.00) | PTGS2AKR1C3AKR1C2PTGS1TSHR | |
| SCHEMBL15116646 | 0.82 | PTGS2 (0.81) | PTGS2AKR1C3AKR1C2PTGS1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220168435-A1 | PROGRAMMABLE POLYMERIC DRUGS | SONY CORPORATION (JP) | 2022-06-02 | — | — | US | disclosed |
| US-11312736-B1 | Programmable polymeric drugs | SONY CORPORATION (JP) | 2022-04-26 | — | — | US | disclosed |
| US-20200360526-A1 | PHOSPHOALKYL POLYMERS COMPRISING BIOLOGICALLY ACTIVE COMPOUNDS | Sony Group Corporation (JP) | 2020-11-19 | — | — | US | disclosed |
| US-20200353094-A1 | PHOSPHOALKYL RIBOSE POLYMERS COMPRISING BIOLOGICALLY ACTIVE COMPOUNDS | Sony Group Corporation (JP) | 2020-11-12 | — | — | US | disclosed |
| US-20200222554-A1 | PROGRAMMABLE DENDRITIC DRUGS | Sony Group Corporation (JP) | 2020-07-16 | — | — | US | disclosed |
| WO-2019071153-A1 | PROGRAMMABLE DENDRITIC DRUGS | SONY CORPORATION (JP) | 2019-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11312736-B1 | Programmable polymeric drugs | NCL, PBRM1, LPXN | PTGS2 3678/4885AKR1C3 2668/4885AKR1C2 3837/4885 |
| US-20200353094-A1 | PHOSPHOALKYL RIBOSE POLYMERS COMPRISING BIOLOGICALLY ACTIVE COMPOUNDS | PARP1, PARP11, PHOSPHO1 | PTGS2 4298/4885AKR1C3 1892/4885AKR1C2 2704/4885 |
| US-20200360526-A1 | PHOSPHOALKYL POLYMERS COMPRISING BIOLOGICALLY ACTIVE COMPOUNDS | PHOSPHO1, PGM2, PHYKPL | PTGS2 3709/4885AKR1C3 2136/4885AKR1C2 3099/4885 |
| US-20220168435-A1 | PROGRAMMABLE POLYMERIC DRUGS | CHRM1, PBRM1, CHRM2 | PTGS2 3893/4885AKR1C3 2495/4885AKR1C2 3796/4885 |
| US-20200222554-A1 | PROGRAMMABLE DENDRITIC DRUGS | CHRM1, TLL1, TEX264 | PTGS2 4578/4885AKR1C3 3785/4885AKR1C2 4401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.