Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKLR | P30613 | 2/20 | 0.33 |
| ▸ | CBLB | Q13191 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 2/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19682359 | 1.00 | PKLR (0.33) | PKLRCBLBTRPV1PRMT5ALOX5 | |
| SCHEMBL22627564 | 0.79 | ALDH1A1 (0.38) | CBLBTRPV1PRMT5ALDH1A1HSD17B10 | |
| SCHEMBL29793781 | 0.79 | CYP1A2 (0.39) | PKLRCBLBPRMT5ALDH1A1HSD17B10 | |
| SCHEMBL13554592 | 0.75 | ALDH1A1 (0.41) | PKLRCBLBTRPV1PRMT5NAMPT | |
| SCHEMBL20889266 | 0.74 | ALOX5 (0.42) | ALOX5KDM4EALDH1A1SLC1A3SLC1A2 | |
| SCHEMBL20889269 | 0.74 | PARP1 (0.46) | KDM4ETDP1ALDH1A1HSD17B10MEN1 | |
| SCHEMBL19682364 | 0.74 | PARP1 (0.46) | KDM4ETDP1ALDH1A1HSD17B10MEN1 | |
| SCHEMBL19682602 | 0.74 | ALOX5 (0.42) | ALOX5KDM4EALDH1A1SLC1A3SLC1A2 | |
| SCHEMBL19682799 | 0.72 | ALDH1A1 (0.38) | CBLBTRPV1PRMT5ALDH1A1HSD17B10 | |
| SCHEMBL21812128 | 0.70 | TRPV1 (0.41) | PKLRCBLBTRPV1PRMT5NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3718545-A1 | ANTITUMOR AGENT | Taiho Pharmaceutical Co., Ltd. (JP) | 2020-10-07 | — | — | EP | disclosed |
| EP-3466934-A1 | SULFONAMIDE COMPOUND OR SALT THEREOF | Taiho Pharmaceutical Co., Ltd. (JP) | 2019-04-10 | — | — | EP | disclosed |