Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20892739 | 0.89 | LMNA (0.49) | KMT2ANPSR1NPC1RAB9AMAPT | |
| SCHEMBL22594431 | 0.85 | KMT2A (0.59) | KMT2ANPSR1PARP10NPC1RAB9A | |
| SCHEMBL20892401 | 0.82 | SRD5A2 (0.58) | PARP10RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL29912311 | 0.78 | LTA4H (0.49) | KMT2ANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL845348 | 0.77 | NPSR1 (0.79) | KMT2ANPSR1PARP10NPC1RAB9A | |
| SCHEMBL22594427 | 0.74 | L3MBTL1 (0.49) | KMT2ANPSR1NPC1RAB9AMAPT | |
| SCHEMBL30776959 | 0.74 | KMT2A (0.69) | KMT2ANPSR1PARP10NPC1RAB9A | |
| SCHEMBL22334720 | 0.73 | L3MBTL1 (0.48) | KMT2ANPSR1NPC1RAB9ATSHR | |
| SCHEMBL22334719 | 0.73 | CYP19A1 (0.48) | KMT2ANPSR1NPC1SMN1; SMN2TSHR | |
| SCHEMBL20892368 | 0.73 | CYP19A1 (0.50) | KMT2ANPSR1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3693365-A1 | EPIDERMAL GROWTH FACTOR RECEPTOR INHIBITORS | Joint Stock Company "Biocad" (RU) | 2020-08-12 | — | — | EP | disclosed |
| WO-2019070167-A1 | EPIDERMAL GROWTH FACTOR RECEPTOR INHIBITORS | ЗАКРЫТОЕ АКЦИОНЕРНОЕ ОБЩЕСТВО "БИОКАД" | 2019-04-11 | — | — | WO | disclosed |