SCHEMBL2089546

SCHEMBL2089546

c1ccc(Cc2ccsc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.57
TAAR1 Q96RJ0 1/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A3 Q01959 1/20 0.46
CYP2E1 P05181 1/20 0.44
CYP2A6 P11509 1/20 0.44
CYP2B6 P20813 1/20 0.44
LTA4H P09960 4/20 0.42
CYP17A1 P05093 1/20 0.41
CYP11B1 P15538 1/20 0.41
CYP11B2 P19099 1/20 0.41
IDO1 P14902 1/20 0.41
TDO2 P48775 1/20 0.41
PTGS1 P23219 1/20 0.41
PTGS2 P35354 1/20 0.41
IDH1 O75874 1/20 0.39
DRD2 P14416 1/20 0.38
DRD3 P35462 1/20 0.38
PRSS1 P07477 1/20 0.38
PRSS2 P07478 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL27477992 0.88 LMNA (0.52) CALM1SLC6A2SLC6A3LTA4HPTGS1
SCHEMBL25364878 0.87 CYP2E1 (0.54) CALM1TAAR1SLC6A2SLC6A3CYP2E1
SCHEMBL9357255 0.87 TAAR1 (0.56) TAAR1SLC6A2SLC6A3LTA4HCYP17A1
SCHEMBL4059254 0.81 TAAR1 (0.58) TAAR1SLC6A2SLC6A3CYP2E1CYP2A6
Benzylamine SCHEMBL6665627 0.77 LOXL2 (0.61) TAAR1SLC6A2SLC6A3CYP2E1CYP2A6
SCHEMBL9732005 0.77 TAAR1 (0.54) TAAR1SLC6A2SLC6A3IDO1DRD2
SCHEMBL1712137 0.77 TAAR1 (0.43) TAAR1SLC6A2SLC6A3LTA4HCYP17A1
SCHEMBL5652167 0.77 ESR1 (0.61) TAAR1LTA4HCYP17A1CYP11B1CYP11B2
SCHEMBL20751464 0.77 IDH1 (0.46) TAAR1CYP2A6LTA4HCYP17A1CYP11B1
SCHEMBL28180421 0.77 LTA4H (0.44) TAAR1LTA4HCYP17A1CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109384779-A One kind can the hypochlorous fluorescent nano probe of ratio test and its preparation method and application 湖南科技大学 2019-02-26 CN claimed
CN-109311942-A Angiotensin-1 receptor antagonists 辉凌公司 2019-02-05 CN claimed
CN-109183081-A A kind of preparation method of additive for electrolytic copper foil and dual light electrolytic copper foil 邵武永太高新材料有限公司 2019-01-11 CN claimed
CN-107236976-B Leveling agent, the metal plating compositions containing it and preparation method, application 上海新阳半导体材料股份有限公司 2018-11-16 CN claimed
CN-106660954-A Substituted azaspiro(4.5)decane derivatives 格吕伦塔尔有限公司 2017-05-10 CN claimed
US-20090014920-A1 POLYMER FILAMENTS MASSEY UNIVERSITY (NZ) 2009-01-15 US claimed
WO-2006001719-A1 POLYMER FILAMENTS MASSEY UNIVERSITY (NZ) 2006-01-05 WO claimed
CN-118852135-A N-acyl sulfonamide compound, preparation method, pharmaceutical composition and application thereof 中国医学科学院药物研究所 2024-10-29 CN disclosed
US-12016312-B2 Animal models, screening methods, and treatment methods for intraocular diseases or disorders Smilebiotek Zhuhai Limited (CN) 2024-06-25 US disclosed
WO-2024073410-A1 TERNARY SOLVENT ELECTROLYTES FOR HIGH VOLTAGE AND HIGH RATE LITHIUM BATTERIES SEPION TECHNOLOGIES, INC. (US) 2024-04-04 WO disclosed
CN-110527069-A A kind of electroluminescent polymer and the preparation method and application thereof UNIV SOUTH CHINA TECH 2019-12-03 CN disclosed
CN-106715396-B Optical activity alpha-trifluoromethyl-beta-aminoacid-derivatives preparation method 公益财团法人微生物化学研究会 2019-09-27 CN disclosed
CN-110177783-A Hormone receptor modulators for the treatment of metabolic conditions and disorders 阿德利克斯股份有限公司 2019-08-27 CN disclosed
EP-0180082-A1 Use of electrically conductive polymers for the absorption of infrared radiation BASF Aktiengesellschaft (DE) 1986-05-07 EP disclosed
EP-0167798-A2 Process for manufacturing p-doped polyheterocycles BASF Aktiengesellschaft (DE) 1986-01-15 EP disclosed
EP-0165753-A2 Herbicidal thiophenesulfonamides and pyridinesulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-12-27 EP disclosed
US-4560534-A Polymer catalyst transducers MILES LABORATORIES, INC. (US) 1985-12-24 US disclosed
EP-0140322-A2 Polymer catalyst transducers and use thereof in test kits for analytical methods MILES INC. (US) 1985-05-08 EP disclosed
US-4390706-A Process for the recovery of pure nitriles DEGUSSA AKTIENGESELLSCHAFT (DE) 1983-06-28 US disclosed
US-4369322-A WITH CYANOGEN CHLORIDE DEGUSSA AG (DE) 1983-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12016312-B2 Animal models, screening methods, and treatment methods for intraocular diseases or disorders MB, MYOC, PDE6A CALM1 3826/4885TAAR1 1137/4885SLC6A2 2914/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.