Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 5/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84733 | 0.78 | ARG1 (0.48) | TP53ALOX15HIF1AHSD17B10ALDH1A1 | |
| Bromide SCHEMBL28351801 | 0.76 | ARG1 (0.47) | TP53ALOX15HIF1AHSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27786790 | 0.76 | ARG1 (0.47) | TP53ALOX15HIF1AHSD17B10ALDH1A1 | |
| SCHEMBL8350047 | 0.74 | TP53 (0.52) | TP53ALOX15HIF1AHSD17B10ALDH1A1 | |
| SCHEMBL9769481 | 0.74 | IDO1 (0.48) | TP53ALOX15HIF1AHSD17B10ALDH1A1 | |
| SCHEMBL2202556 | 0.73 | ALDH1A1 (0.52) | TP53ALOX15HIF1AHSD17B10ALDH1A1 | |
| SCHEMBL27479818 | 0.73 | ALDH1A1 (0.39) | TP53ALOX15HIF1AHSD17B10ALDH1A1 | |
| SCHEMBL1487928 | 0.73 | TNIK (0.41) | TP53ALOX15HIF1AHSD17B10ALDH1A1 | |
| SCHEMBL10001895 | 0.73 | HSD17B10 (0.50) | TP53ALOX15HIF1AHSD17B10ALDH1A1 | |
| SCHEMBL13145946 | 0.73 | ALOX15 (0.50) | TP53ALOX15HIF1AHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331139-B1 | POLYMERIC ALPHA-HYDROXY ALDEHYDE AND KETONE REAGENTS AND CONJUGATION METHOD | NEKTAR THERAPEUTICS (US) | 2019-04-17 | — | — | EP | disclosed |