Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13300837 | 0.83 | SMN1; SMN2 (0.40) | KDM4ETDP1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11567188 | 0.80 | KDM4E (0.44) | KDM4ETDP1NTRK1HPGDSMN1; SMN2 | |
| SCHEMBL14304002 | 0.79 | PTGS2 (0.40) | PTGS1PTGS2ALDH1A1PKMRAB9A | |
| SCHEMBL6511715 | 0.79 | IDO1 (0.40) | KDM4ESMN1; SMN2PTGS2MEN1KMT2A | |
| SCHEMBL10280239 | 0.79 | FFAR4 (0.40) | KDM4EPTGS1PTGS2L3MBTL1LMNA | |
| SCHEMBL27409873 | 0.79 | PDPK1 (0.41) | PTGS2MEN1KMT2APDPK1ALDH1A1 | |
| SCHEMBL2092341 | 0.77 | ADORA2A (0.46) | KDM4EMEN1KMT2ALMNAMAPT | |
| SCHEMBL543734 | 0.76 | ADORA1 (0.47) | KDM4EHPGDSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL926914 | 0.76 | KDM4E (0.55) | KDM4EALOX15PDPK1ALDH1A1MAPT | |
| SCHEMBL23618656 | 0.75 | AKT1 (0.40) | KDM4ETDP1NTRK1ALOX15MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4925901-A | STORAGE STAABILITY, ONIUM ION CATALYST | THE DOW CHEMICAL COMPANY (US) | 1990-05-15 | — | — | US | claimed |
| CN-116425698-B | Methylthiazole compound and preparation method and application thereof | 广东省科学院微生物研究所(广东省微生物分析检测中心) | 2023-08-29 | — | — | CN | disclosed |
| CN-116425698-A | Methylthiazole compound and preparation method and application thereof | 广东省科学院微生物研究所(广东省微生物分析检测中心) | 2023-07-14 | — | — | CN | disclosed |
| EP-3265447-B1 | BENZOXAZINE LOW TEMPERATURE CURABLE COMPOSITION | HUNTSMAN ADVANCED MAT AMERICAS LLC (US) | 2023-03-01 | — | — | EP | disclosed |
| US-20220259180-A1 | BROAD SPECTRUM ANTIVIRAL COMPOUNDS TARGETING THE SKI COMPLEX | UNIVERSITY OF MARYLAND, BALTIMORE | 2022-08-18 | — | — | US | disclosed |
| CN-107428708-B | Benzoxazine low temperature curable compositions | 亨斯迈先进材料美国有限责任公司 | 2021-11-09 | — | — | CN | disclosed |
| US-20180030264-A1 | Benzoxazine Low Temperature Curable Composition | HUNTSMAN ADVANCED MATERIALS AMERICAS LLC | 2018-02-01 | — | — | US | disclosed |
| EP-3265447-A1 | BENZOXAZINE LOW TEMPERATURE CURABLE COMPOSITION | Huntsman Advanced Materials Americas LLC (US) | 2018-01-10 | — | — | EP | disclosed |
| WO-2017125060-A1 | NITROGENOUS HETEROCYCLIC AMIDE DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL APPLICATION | 四川海思科制药有限公司 | 2017-07-27 | — | — | WO | disclosed |
| US-8980837-B2 | Inhibitors of IAP | GENENTECH, INC. (US) | 2015-03-17 | — | — | US | disclosed |
| CN-1056699-A | Latent catalysts and cure-inhibited epoxy resin compositions and laminates made therefrom | DOW CHEMICAL CO (US) | 1991-12-04 | — | — | CN | disclosed |
| EP-0458502-A2 | Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom | THE DOW CHEMICAL COMPANY (US) | 1991-11-27 | — | — | EP | disclosed |
| US-4925901-A | STORAGE STAABILITY, ONIUM ION CATALYST | THE DOW CHEMICAL COMPANY (US) | 1990-05-15 | — | — | US | disclosed |
| CN-1006386-B | PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER | SHINETSU CHEM IND CO (JP) | 1990-01-10 | — | — | CN | disclosed |
| EP-0328020-A2 | Use of a catalyst in epoxy compositions | THE DOW CHEMICAL COMPANY (US) | 1989-08-16 | — | — | EP | disclosed |
| EP-0172427-B1 | PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER | Shin-Etsu Chemical Co., Ltd. (JP) | 1989-07-05 | — | — | EP | disclosed |
| US-4758639-A | Process for production of vinyl polymer | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-07-19 | — | — | US | disclosed |
| US-4757124-A | Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-07-12 | — | — | US | disclosed |
| CN-85107531-A | Process for producing vinyl chloride polymer | — | 1987-01-21 | — | — | CN | disclosed |
| EP-0172427-A2 | Process for production of vinyl chloride polymer | Shin-Etsu Chemical Co., Ltd. (JP) | 1986-02-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220259180-A1 | BROAD SPECTRUM ANTIVIRAL COMPOUNDS TARGETING THE SKI COMPLEX | EIF2AK2, MAVS, IRF3 | KDM4E 2279/4885TDP1 981/4885NTRK1 4662/4885 |
| US-20180030264-A1 | Benzoxazine Low Temperature Curable Composition | CRYZ, PIEZO1, PSMD12 | KDM4E 471/4885TDP1 1590/4885NTRK1 2943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.