SCHEMBL2089672

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6236937	0.83	IDO1 (0.57)	IDO1MAPTSIGMAR1
	SCHEMBL6022845	0.79	IDO1 (0.37)	IDO1GRM2GRM3KDM5AKDM5B
	SCHEMBL10823078	0.77	PNMT (0.45)	IDO1GRM2GRM3MAPTMAPK1
	SCHEMBL3746892	0.77	MAPT (0.45)	IDO1GRM2GRM3MAPTMAPK1
	SCHEMBL22889496	0.76	IDO1 (0.42)	IDO1GRM2GRM3KDM5AKDM5B
	SCHEMBL27532057	0.75	IDO1 (0.39)	IDO1GRM2GRM3KDM5AKDM5B
	SCHEMBL5977520	0.75	IDO1 (0.50)	IDO1MAPTMAPK1
	SCHEMBL5981060	0.75	IDO1 (0.50)	IDO1
	SCHEMBL95960	0.73	GPR84 (0.50)	GPR84HRH3PPARGPPARA
	SCHEMBL20378901	0.73	KDM5A (0.38)	GRM2GRM3KDM5AKDM5BDRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.