Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823078 | 0.83 | PNMT (0.45) | MAPTMAPK1PNMTTAAR1GRM2 | |
| SCHEMBL151278 | 0.82 | PIK3CA (0.44) | MAPTPNMTTAAR1MEN1PLA2G1B | |
| SCHEMBL31634179 | 0.79 | MAPT (0.42) | MAPTMAPK1PNMTTAAR1GRM2 | |
| SCHEMBL4524759 | 0.79 | MAPT (0.42) | MAPTMAPK1PNMTTAAR1GRM2 | |
| SCHEMBL93982 | 0.78 | IDO1 (0.58) | PNMTTAAR1IDO1SLC6A3SLC6A4 | |
| SCHEMBL126440 | 0.78 | HTT (0.45) | — | |
| SCHEMBL119714 | 0.77 | CYP4F2 (0.42) | MAPTMAPK1PNMTTAAR1GRM2 | |
| SCHEMBL257064 | 0.77 | TRPA1 (0.41) | MAPTMAPK1PNMTTAAR1GRM2 | |
| SCHEMBL2092845 | 0.77 | MAPT (0.41) | MAPTMAPK1PNMTTAAR1GRM2 | |
| SCHEMBL295912 | 0.77 | PNMT (0.48) | MAPTMAPK1PNMTTAAR1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019025153-A1 | USE OF SUBSTITUTED N-SULFONYL-N'-ARYL DIAMINOALKANES AND N-SULFONYL-N'-HETEROARYL DIAMINOALKANES OR SALTS THEREOF FOR INCREASING THE STRESS TOLERANCE IN PLANTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-02-07 | — | — | WO | claimed |
| WO-2019025153-A1 | USE OF SUBSTITUTED N-SULFONYL-N'-ARYL DIAMINOALKANES AND N-SULFONYL-N'-HETEROARYL DIAMINOALKANES OR SALTS THEREOF FOR INCREASING THE STRESS TOLERANCE IN PLANTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-02-07 | — | — | WO | disclosed |
| EP-3129025-A1 | PROCESS FOR THE MANUFACTURING OF MEDICAMENTS | Genentech, Inc. (US) | 2017-02-15 | — | — | EP | disclosed |
| WO-2016095088-A1 | ERK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-06-23 | — | — | WO | disclosed |
| WO-2015154674-A1 | PROCESS FOR THE MANUFACTURING OF MEDICAMENTS | GENENTECH, INC. (US) | 2015-10-15 | — | — | WO | disclosed |
| EP-2887802-A2 | METHODS OF SOIL PEST CONTROL | Syngenta Participations AG (CH) | 2015-07-01 | — | — | EP | disclosed |
| WO-2014029706-A2 | METHODS OF CONTROLLING INSECTS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-27 | — | — | WO | disclosed |
| WO-2014029710-A2 | METHODS OF SOIL PEST CONTROL | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-27 | — | — | WO | disclosed |
| WO-2014029707-A1 | METHODS OF CONTROLLING INSECTS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-27 | — | — | WO | disclosed |
| WO-2014029708-A1 | METHODS OF CONTROLLING INSECTS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-27 | — | — | WO | disclosed |
| WO-2014019609-A1 | METHODS OF PEST CONTROL IN SOYBEAN | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-06 | — | — | WO | disclosed |
| US-8426631-B2 | Fungicidal compounds, method for the production thereof, and use thereof to combat damaging fungi, and agents comprising the same | BASF SE (DE) | 2013-04-23 | — | — | US | disclosed |
| US-20100304966-A1 | Fungicidal Compounds, Method For the Production Thereof, And Use Thereof To Combat Damaging Fungi, And Agents Comprising The Same | BASF SE (DE) | 2010-12-02 | — | — | US | disclosed |
| CN-1809362-A | Substituted 1,4-diazepines and uses thereof | JOHNSON & JOHNSON (US) | 2006-07-26 | — | — | CN | disclosed |
| US-4053478-A | ARTERIOSCLEROSIS, THROMBOSIS, HYPERTENSION | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JA) | 1977-10-11 | — | — | US | disclosed |
| US-4012412-A | USEFUL IN THE TREATMENT OF HYPERTENSION, ARTERIOSCLEROSIS, AND THROMBOSIS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JA) | 1977-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100304966-A1 | Fungicidal Compounds, Method For the Production Thereof, And Use Thereof To Combat Damaging Fungi, And Agents Comprising The Same | CYP51A1, ERG28, CAT | MAPT 2257/4885MAPK1 1845/4885PNMT 591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.