Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 9/20 | 0.62 |
| ▸ | CA1 | P00915 | 8/20 | 0.62 |
| ▸ | CA12 | O43570 | 5/20 | 0.62 |
| ▸ | CA9 | Q16790 | 5/20 | 0.62 |
| ▸ | CA5A | P35218 | 3/20 | 0.62 |
| ▸ | CA7 | P43166 | 3/20 | 0.62 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.62 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.56 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30098967 | 0.84 | L3MBTL1 (0.60) | L3MBTL1PTGS2 | |
| SCHEMBL456924 | 0.78 | L3MBTL1 (0.69) | MEN1KMT2AALDH1A1L3MBTL1KDM4E | |
| Hydrochloric Acid SCHEMBL6298735 | 0.77 | L3MBTL1 (0.67) | MEN1KMT2AALDH1A1L3MBTL1KDM4E | |
| SCHEMBL4060324 | 0.77 | CA2 (0.62) | MEN1KMT2AALDH1A1CA2 | |
| SCHEMBL2716691 | 0.76 | L3MBTL1 (0.70) | MEN1KMT2AALDH1A1L3MBTL1KDM4E | |
| SCHEMBL28225354 | 0.76 | L3MBTL1 (0.61) | MEN1KMT2AALDH1A1CA2CA1 | |
| SCHEMBL7955725 | 0.76 | L3MBTL1 (0.65) | MEN1KMT2AALDH1A1L3MBTL1KDM4E | |
| SCHEMBL8322277 | 0.75 | L3MBTL1 (0.69) | MEN1KMT2AALDH1A1L3MBTL1KDM4E | |
| SCHEMBL8782898 | 0.75 | L3MBTL1 (0.69) | MEN1KMT2AALDH1A1L3MBTL1KDM4E | |
| SCHEMBL1958230 | 0.74 | MAPT (0.56) | MEN1KMT2ACA2CA1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019075394-A1 | COMPOUNDS FOR TREATMENT OF EMOTIONAL/PSYCHOLOGICAL SYMPTOMS IN FRAGILE X SYNDROME | VANDERKLISH PETER (US) | 2019-04-18 | — | — | WO | disclosed |
| CN-1249039-C | Inhibitors of 11 beta-hydroxysteroid dehydrogenase type I | BIOVITRUM AB (SE) | 2006-04-05 | — | — | CN | disclosed |
| CN-1438997-A | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type I | BIOVITRUM AB (SE) | 2003-08-27 | — | — | CN | disclosed |