Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.69 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2716691 | 0.82 | L3MBTL1 (0.70) | L3MBTL1KCNH3LMNASMN1; SMN2HPGD | |
| SCHEMBL456924 | 0.81 | L3MBTL1 (0.69) | L3MBTL1KCNH3SMN1; SMN2POLBPTPN1 | |
| SCHEMBL8782898 | 0.81 | L3MBTL1 (0.69) | L3MBTL1KCNH3LMNASMN1; SMN2POLB | |
| Hydrochloric Acid SCHEMBL6298735 | 0.80 | L3MBTL1 (0.67) | L3MBTL1KCNH3SMN1; SMN2POLBPTPN1 | |
| SCHEMBL2719222 | 0.79 | L3MBTL1 (0.66) | L3MBTL1KCNH3SMN1; SMN2PTPN1PTPN11 | |
| SCHEMBL6495851 | 0.79 | KCNH3 (0.50) | L3MBTL1KCNH3LMNASMN1; SMN2HPGD | |
| SCHEMBL7955725 | 0.79 | L3MBTL1 (0.65) | L3MBTL1KCNH3LMNASMN1; SMN2POLB | |
| SCHEMBL15456012 | 0.78 | L3MBTL1 (0.64) | L3MBTL1KCNH3SMN1; SMN2HPGDPOLB | |
| SCHEMBL6798736 | 0.77 | L3MBTL1 (0.63) | L3MBTL1KCNH3LMNASMN1; SMN2HPGD | |
| SCHEMBL14849565 | 0.77 | MAPT (0.63) | L3MBTL1LMNASMN1; SMN2HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635018-B1 | 4-(1H-2-METHYLIMIDAZO[4,5-c]PYRIDINYLMETHYL)PHENYLSULPHONAMIDE DERIVATIVES AS ANTAGONISTS OF PAF | BRITISH BIO TECHNOLOGY (GB) | 1999-12-22 | — | — | EP | disclosed |
| US-5516783-A | PLATELET ACTIVATING FACTOR | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-05-14 | — | — | US | disclosed |
| EP-0635018-A1 | 4-(1H-2-METHYLIMIDAZO 4,5-c]PYRIDINYLMETHYL)PHENYLSULPHONAMIDE DERIVATIVES AS ANTAGONISTS OF PAF | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993016075-A1 | 4-(1H-2-METHYLIMIDAZO[4,5-c]PYRIDINYLMETHYL)PHENYLSULPHONAMIDE DERIVATIVES AS ANTAGONISTS OF PAF | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-08-19 | — | — | WO | disclosed |