Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 3/20 | 0.40 |
| ▸ | CTSS | P25774 | 3/20 | 0.40 |
| ▸ | CTSK | P43235 | 3/20 | 0.40 |
| ▸ | KIFC1 | Q9BW19 | 6/20 | 0.38 |
| ▸ | GCGR | P47871 | 3/20 | 0.37 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.37 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.37 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.37 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.37 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.37 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.37 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.37 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.37 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16305824 | 0.91 | GCGR (0.47) | L3MBTL1CTSBCTSSCTSKKIFC1 | |
| SCHEMBL20900666 | 0.84 | PLG (0.48) | L3MBTL1CTSBCTSSCTSKKIFC1 | |
| SCHEMBL22756229 | 0.83 | L3MBTL1 (0.50) | L3MBTL1CTSBCTSSCTSKKIFC1 | |
| SCHEMBL20900619 | 0.82 | PLG (0.51) | L3MBTL1KIFC1GCGRKLKB1 | |
| SCHEMBL19485577 | 0.82 | KIFC1 (0.45) | L3MBTL1CTSBCTSSCTSKKIFC1 | |
| SCHEMBL22384407 | 0.80 | L3MBTL1 (0.45) | L3MBTL1CTSBCTSSCTSKKIFC1 | |
| SCHEMBL16306220 | 0.79 | GCGR (0.56) | L3MBTL1CTSBCTSSCTSKKIFC1 | |
| SCHEMBL16305989 | 0.79 | GCGR (0.47) | L3MBTL1CTSBCTSSCTSKKIFC1 | |
| SCHEMBL22384055 | 0.79 | L3MBTL1 (0.42) | L3MBTL1CTSBCTSSCTSKKIFC1 | |
| SCHEMBL16305939 | 0.79 | GCGR (0.48) | L3MBTL1CTSBCTSSCTSKKIFC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10259823-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2019-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10259823-B2 | GLP-1 receptor modulators | GLP1R, GIPR, GCGR | L3MBTL1 579/4885CTSB 1992/4885CTSS 3308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.