Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.39 |
| ▸ | CTSA | P10619 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12418419 | 0.85 | APP (0.46) | MAPTAPPPSEN1PSEN2APH1B | |
| SCHEMBL12618445 | 0.83 | LMNA (0.42) | APPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL24766983 | 0.81 | CA3 (0.44) | PTPN1 | |
| SCHEMBL12570861 | 0.79 | MAPK14 (0.40) | MAPK14MAPTAPPPSEN1PSEN2 | |
| SCHEMBL12648771 | 0.78 | CTSA (0.37) | DPP4DPP7MAPK14CTSAIDH1 | |
| SCHEMBL1047374 | 0.78 | ACHE (0.50) | MAPK14GCGR | |
| SCHEMBL7556230 | 0.78 | TAAR1 (0.50) | MAPK14MAPTPTPN1APPCYP3A4 | |
| SCHEMBL12570868 | 0.77 | AKR1C3 (0.50) | MAPTAPPPSEN1PSEN2APH1B | |
| SCHEMBL13524522 | 0.77 | LMNA (0.50) | MAPTPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2662627 | 0.77 | CYP17A1 (0.47) | MAPK14MAPTMAPK13GCGRMAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220152008-A1 | Enantiomers Of Substituted Thiazoles As Antiviral Compounds | INNOVATIVE MOLECULES GMBH (DE) | 2022-05-19 | — | — | US | disclosed |
| US-20200289486-A1 | Enantiomers Of Substituted Thiazoles As Antiviral Compounds | INNOVATIVE MOLECULES GMBH (DE) | 2020-09-17 | — | — | US | disclosed |
| US-20200148652-A1 | Aminothiazole Derivatives Useful As Antiviral Agents | INNOVATIVE MOLECULES GMBH (DE) | 2020-05-14 | — | — | US | disclosed |
| US-10590094-B2 | Aminothiazole derivatives useful as antiviral agents | INNOVATIVE MOLECULES GMBH (DE) | 2020-03-17 | — | — | US | disclosed |
| US-20190112285-A1 | Aminothiazole Derivatives Useful As Antiviral Agents | INNOVATIVE MOLECULES GMBH (DE) | 2019-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200148652-A1 | Aminothiazole Derivatives Useful As Antiviral Agents | MAVS, EIF2AK2, SARS1 | DPP4 40/4885DPP7 76/4885MAPK14 1647/4885 |
| US-20190112285-A1 | Aminothiazole Derivatives Useful As Antiviral Agents | MAVS, EIF2AK2, SARS1 | DPP4 34/4885DPP7 71/4885MAPK14 1843/4885 |
| US-20220152008-A1 | Enantiomers Of Substituted Thiazoles As Antiviral Compounds | EIF2AK2, MAVS, ZC3HAV1 | DPP4 14/4885DPP7 25/4885MAPK14 3104/4885 |
| US-20200289486-A1 | Enantiomers Of Substituted Thiazoles As Antiviral Compounds | EIF2AK2, MAVS, ZC3HAV1 | DPP4 14/4885DPP7 25/4885MAPK14 3104/4885 |
| US-10590094-B2 | Aminothiazole derivatives useful as antiviral agents | MAVS, EIF2AK2, SARS1 | DPP4 34/4885DPP7 71/4885MAPK14 1843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.