Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 16/20 | 0.61 |
| ▸ | CA9 | Q16790 | 14/20 | 0.61 |
| ▸ | CA1 | P00915 | 11/20 | 0.61 |
| ▸ | CA7 | P43166 | 8/20 | 0.61 |
| ▸ | CA12 | O43570 | 9/20 | 0.59 |
| ▸ | CA5A | P35218 | 4/20 | 0.57 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.57 |
| ▸ | NOS3 | P29474 | 1/20 | 0.55 |
| ▸ | NOS1 | P29475 | 1/20 | 0.55 |
| ▸ | NOS2 | P35228 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.55 |
| ▸ | CA6 | P23280 | 3/20 | 0.54 |
| ▸ | CA4 | P22748 | 2/20 | 0.54 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL202948 | 0.81 | CA2 (0.81) | CA2CA9CA1CA7CA12 | |
| SCHEMBL5827867 | 0.78 | CA2 (0.63) | CA2CA9CA1CA7CA12 | |
| SCHEMBL18856575 | 0.78 | CA2 (0.57) | CA2CA9CA1CA7CA12 | |
| SCHEMBL6849911 | 0.78 | CA2 (0.61) | CA2CA9CA1CA7CA12 | |
| SCHEMBL14467520 | 0.78 | CA2 (0.57) | CA2CA9CA1CA7CA12 | |
| SCHEMBL16712211 | 0.77 | ALDH1A1 (0.41) | CA2CA9CA1CA7CA12 | |
| SCHEMBL11921694 | 0.75 | ALDH1A1 (0.50) | CA2CA9CA1CA7CA12 | |
| SCHEMBL13632324 | 0.75 | ALDH1A1 (0.39) | CA2CA9CA1CA7CA12 | |
| SCHEMBL5316865 | 0.75 | ENPP2 (0.52) | PTGS2TSHR | |
| SCHEMBL3872941 | 0.75 | POLB (0.59) | CA2CA9CA1CA7CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019075357-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2019-04-18 | — | — | WO | disclosed |
| CN-105452398-B | Composition for ink, ink jet recording method and tingle body using this composition for ink | 日本化药株式会社 | 2018-07-10 | — | — | CN | disclosed |
| CN-102026989-B | Pharmaceutical composition for preventing or treating protozoal diseases, containing benzo [ a ] phenoxazine compound as active ingredient | HOSHI UNIVERSITY | 2013-03-27 | — | — | CN | disclosed |
| CN-102026989-A | Pharmaceutical composition for preventing or treating protozoal diseases, containing benzo [ a ] phenoxazine compound as active ingredient | HOSHI UNIVERSITY | 2011-04-20 | — | — | CN | disclosed |