SCHEMBL3872941

SCHEMBL3872941

O=Nc1ccc(S(=O)(=O)O)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.59
CYP2D6 P10635 1/20 0.59
LMNA P02545 1/20 0.54
ALDH1A1 P00352 5/20 0.52
TSHR P16473 4/20 0.52
NT5E P21589 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.50
TDP1 Q9NUW8 2/20 0.46
HSD17B10 Q99714 4/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
RPS6KA3 P51812 1/20 0.44
PHLPP2 Q6ZVD8 1/20 0.41
TP53 P04637 1/20 0.39
MAPK1 P28482 1/20 0.39
HIF1A Q16665 1/20 0.39
KDM4E B2RXH2 1/20 0.39
ATIC P31939 1/20 0.38
CA2 P00918 2/20 0.38
CA7 P43166 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18624977 0.82 POLB (0.83) POLBCYP2D6LMNAALDH1A1TSHR
SCHEMBL28560987 0.82 POLB (0.83) POLBCYP2D6LMNAALDH1A1TSHR
SCHEMBL150334 0.81 LMNA (0.77) POLBCYP2D6LMNAALDH1A1TSHR
SCHEMBL10590842 0.80 POLB (0.59) POLBCYP2D6LMNAALDH1A1TSHR
SCHEMBL14405865 0.79 SNCA (0.49) POLBCYP2D6LMNAALDH1A1TSHR
SCHEMBL1807437 0.78 POLB (0.57) POLBCYP2D6LMNAALDH1A1TSHR
SCHEMBL5573269 0.78 POLB (0.57) POLBCYP2D6LMNAALDH1A1TSHR
SCHEMBL8913153 0.78 POLB (0.57) POLBCYP2D6LMNAALDH1A1TSHR
SCHEMBL8916595 0.78 POLB (0.57) POLBCYP2D6LMNAALDH1A1TSHR
SCHEMBL14527054 0.78 POLB (0.57) POLBCYP2D6LMNAALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108473492-A Novel crystalline salt forms of 3- (1,2, 4-triazolo [4,3-a ] pyridin-3-ylethynyl) -4-methyl-N- (4- ((4-methylpiperazin-1-yl) methyl) -3-trifluoromethylphenyl) benzamide for medical applications 融合制药有限责任公司 2018-08-31 CN disclosed
EP-3279734-B1 POSITIVE RESIST COMPOSITION, RESIST PATTERN FORMING PROCESS, AND PHOTOMASK BLANK SHINETSU CHEMICAL CO (JP) 2018-07-25 EP disclosed
EP-3279734-A1 POSITIVE RESIST COMPOSITION, RESIST PATTERN FORMING PROCESS, AND PHOTOMASK BLANK Shin-Etsu Chemical Co., Ltd. (JP) 2018-02-07 EP disclosed
EP-2701673-B1 DYE COMPOSITION USING A PARTICULAR PHENOLIC COUPLER IN A MEDIUM RICH IN FATTY SUBSTANCES, PROCESSES AND DEVICES L'ORÉAL (FR) 2017-09-13 EP disclosed
EP-1847568-B1 THERMOSETTING RESIN COMPOSITION, THERMOSETTING-RESIN MOLDING MATERIAL, AND CURED OBJECT OBTAINED THEREFROM SUMITOMO BAKELITE CO (JP) 2015-05-20 EP disclosed
CN-101065445-B Thermosetting resin composition, thermosetting-resin molding material, and cured object obtained therefrom SUMITOMO BAKELITE CO 2011-05-11 CN disclosed
US-7541410-B2 Thermosetting resin composition, thermosetting resin molding compound and cured product thereof SUMITOMO BAKELITE CO., LTD. (JP) 2009-06-02 US disclosed
US-20080139757-A1 Thermosetting Resin Composition, Thermosetting Resin Molding Compound And Cured Product Thereof SUMITOMO BAKELITE CO., LTD. (JP) 2008-06-12 US disclosed
CN-101065445-A Thermosetting resin composition, thermosetting-resin molding material, and cured object obtained therefrom SUMITOMO BAKELITE CO (JP) 2007-10-31 CN disclosed
EP-1847568-A1 THERMOSETTING RESIN COMPOSITION, THERMOSETTING-RESIN MOLDING MATERIAL, AND CURED OBJECT OBTAINED THEREFROM Sumitomo Bakelite Company, Limited (JP) 2007-10-24 EP disclosed
US-7094351-B2 Purification of substances by reaction affinity chromatography CORCORAN ROBERT C 2006-08-22 US disclosed
US-20020100727-A1 Purification of substances by reaction affinity chromatography CORCORAN ROBERT C (US) 2002-08-01 US disclosed
WO-2002030542-A2 PURIFICATION OF SUBSTANCE BY REACTION AFFINITY CHROMATOGRAPHY CORCORAN ROBERT (US) 2002-04-18 WO disclosed
EP-0970148-A1 OLIGOMERIC AZO DYES BASF AKTIENGESELLSCHAFT (DE) 2000-01-12 EP disclosed
WO-1998041581-A1 OLIGOMERIC AZO DYES BASF AKTIENGESELLSCHAFT (DE) 1998-09-24 WO disclosed