Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ESRRG | P62508 | 1/20 | 0.35 |
| ▸ | USP5 | P45974 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19101609 | 0.79 | TSHR (0.32) | SMN1; SMN2MAPTALDH1A1HPGDRAB9A | |
| SCHEMBL26741241 | 0.78 | APP (0.36) | ALDH1A1HPGD | |
| SCHEMBL24728527 | 0.76 | L3MBTL1 (0.38) | HTTSMN1; SMN2ALDH1A1L3MBTL1GAA | |
| SCHEMBL14079878 | 0.75 | HTT (0.37) | HTTCYP2C9SMN1; SMN2ALDH1A1USP5 | |
| SCHEMBL23486953 | 0.74 | MAPK13 (0.42) | HTTCYP2C9SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL21943809 | 0.69 | CHRM2 (0.43) | HTTCYP2C9MAPTALDH1A1MITF | |
| SCHEMBL20901312 | 0.65 | KDM4E (0.47) | HTTMAPTALDH1A1RAB9AMEN1 | |
| SCHEMBL27398572 | 0.65 | CYP19A1 (0.40) | CYP2C9SMN1; SMN2MAPTALDH1A1HPGD | |
| SCHEMBL24227171 | 0.64 | HTT (0.39) | HTTCYP2C9SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL2098167 | 0.64 | HTT (0.50) | HTTCYP2C9SMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10590094-B2 | Aminothiazole derivatives useful as antiviral agents | INNOVATIVE MOLECULES GMBH (DE) | 2020-03-17 | — | — | US | disclosed |
| US-20190112285-A1 | Aminothiazole Derivatives Useful As Antiviral Agents | INNOVATIVE MOLECULES GMBH (DE) | 2019-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190112285-A1 | Aminothiazole Derivatives Useful As Antiviral Agents | MAVS, EIF2AK2, SARS1 | HTT 3764/4885CYP2C9 2496/4885SMN1; SMN2 4214/4885 |
| US-10590094-B2 | Aminothiazole derivatives useful as antiviral agents | MAVS, EIF2AK2, SARS1 | HTT 3764/4885CYP2C9 2496/4885SMN1; SMN2 4214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.