Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MPO | P05164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19101609 | 0.71 | TSHR (0.32) | L3MBTL1LMNAALDH1A1KDM4ECYP3A4 | |
| SCHEMBL26741241 | 0.70 | APP (0.36) | ALDH1A1CYP3A4 | |
| SCHEMBL20904157 | 0.69 | HTT (0.38) | L3MBTL1LMNAALDH1A1CYP2C9MAPT | |
| SCHEMBL24728527 | 0.68 | L3MBTL1 (0.38) | L3MBTL1MPOALDH1A1KDM4EHDAC3 | |
| SCHEMBL23486953 | 0.67 | MAPK13 (0.42) | L3MBTL1LMNAALDH1A1HDAC3HDAC1 | |
| SCHEMBL8326406 | 0.66 | CHRM2 (0.66) | CHRM2L3MBTL1LMNAMPOALDH1A1 | |
| SCHEMBL4599034 | 0.65 | CHRM2 (0.64) | CHRM2L3MBTL1LMNAMPOALDH1A1 | |
| SCHEMBL8851178 | 0.65 | LMNA (0.67) | CHRM2L3MBTL1LMNAMPOALDH1A1 | |
| SCHEMBL29337015 | 0.65 | SMN1; SMN2 (0.36) | LMNAALDH1A1KDM4EHDAC3HDAC1 | |
| SCHEMBL19495183 | 0.64 | GAA (0.40) | LMNAALDH1A1HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10869866-B2 | Benzathine analogs | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2020-12-22 | — | — | US | disclosed |
| US-20200113900-A1 | BENZATHINE ANALOGS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200113900-A1 | BENZATHINE ANALOGS | HDAC10, CFTR, HBB | CHRM2 451/4885L3MBTL1 1666/4885LMNA 2851/4885 |
| US-10869866-B2 | Benzathine analogs | HDAC10, CFTR, HBB | CHRM2 451/4885L3MBTL1 1666/4885LMNA 2851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.