Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 4/20 | 0.51 |
| ▸ | DRD3 | P35462 | 4/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 3/20 | 0.50 |
| ▸ | CHKA | P35790 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14922286 | 0.94 | SMN1; SMN2 (0.59) | NPC1RAB9ASMN1; SMN2PKMCYP2C19 | |
| SCHEMBL13727501 | 0.83 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2CYP2C19ADRA2C | |
| SCHEMBL20000624 | 0.83 | DRD2 (0.50) | NPC1RAB9ASMN1; SMN2PKMDRD2 | |
| SCHEMBL23646854 | 0.79 | MAPT (0.57) | NPC1RAB9ASMN1; SMN2PKMDRD2 | |
| SCHEMBL30061277 | 0.79 | MAPT (0.57) | NPC1RAB9ASMN1; SMN2PKMDRD2 | |
| SCHEMBL24434520 | 0.78 | CMA1 (0.56) | NPC1RAB9ADRD2DRD3DRD4 | |
| SCHEMBL20907277 | 0.76 | CHKA (0.62) | NPC1RAB9ASMN1; SMN2ADRA2CCHKA | |
| SCHEMBL4950509 | 0.76 | HTR1A (0.53) | DRD2DRD3HTR1AADRA2AADRA2C | |
| SCHEMBL5235512 | 0.75 | TGFBR1 (0.51) | NPC1RAB9ADRD2DRD3HTR1A | |
| SCHEMBL15981860 | 0.75 | DRD2 (0.52) | NPC1RAB9ASMN1; SMN2DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019073251-A1 | LYSYL OXIDASE INHIBITORS | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2019-04-18 | — | — | WO | disclosed |