SCHEMBL2090779

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL542677	0.88	MEN1 (0.53)	ENPP2ATXN2HPGDSMN1; SMN2HRH3
	SCHEMBL543231	0.87	MEN1 (0.55)	ENPP2ATXN2HPGDSMN1; SMN2HRH3
	SCHEMBL2093190	0.85	ENPP2 (0.50)	ENPP2ATXN2SMN1; SMN2HRH3
	SCHEMBL2092511	0.83	SMN1; SMN2 (0.44)	HPGDSMN1; SMN2HRH3MEN1KMT2A
	SCHEMBL2099149	0.83	ENPP2 (0.46)	ENPP2ATXN2HPGDSMN1; SMN2MEN1
	SCHEMBL2097232	0.83	GRIN2B (0.54)	SMN1; SMN2MEN1KMT2AGRIN2BNPSR1
	SCHEMBL2093890	0.83	MEN1 (0.44)	SMN1; SMN2HRH3MEN1KMT2AGRIN2B
	SCHEMBL5542597	0.83	MEN1 (0.59)	SMN1; SMN2MEN1KMT2AGRIN2BNPSR1
	SCHEMBL2093956	0.81	GRIN2B (0.53)	HPGDSMN1; SMN2HRH3MEN1KMT2A
	SCHEMBL5537108	0.79	ENPP2 (0.49)	ENPP2ATXN2HPGDSMN1; SMN2HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.