SCHEMBL2099149

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2093890	0.86	MEN1 (0.44)	NPC1RAB9AKMT2AMEN1NPSR1
	SCHEMBL2092511	0.86	SMN1; SMN2 (0.44)	ALDH1A1NPC1RAB9AMAPTKMT2A
	SCHEMBL2097232	0.86	GRIN2B (0.54)	ALDH1A1NPC1RAB9AKMT2AMEN1
	SCHEMBL5542597	0.86	MEN1 (0.59)	NPC1RAB9AKMT2AMEN1NPSR1
	SCHEMBL2091114	0.86	ENPP2 (0.49)	ENPP2ATXN2ALDH1A1NPC1RAB9A
	SCHEMBL543584	0.86	RAB9A (0.58)	ENPP2ATXN2ALDH1A1NPC1RAB9A
	SCHEMBL2093956	0.84	GRIN2B (0.53)	ALDH1A1MAPTKMT2AMEN1NPSR1
	SCHEMBL2090779	0.83	ENPP2 (0.48)	ENPP2ATXN2NPC1RAB9AMAPT
	SCHEMBL2096197	0.82	ENPP2 (0.50)	ENPP2ATXN2MAPTKMT2AMEN1
	SCHEMBL2093190	0.81	ENPP2 (0.50)	ENPP2ATXN2ALDH1A1SMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.