Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.61 |
| ▸ | NCEH1 | Q6PIU2 | 9/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2090833 | 0.85 | SIGMAR1 (0.59) | SIGMAR1NCEH1LMNA | |
| SCHEMBL11570035 | 0.82 | SIGMAR1 (0.56) | SIGMAR1NCEH1TSHRALDH1A1 | |
| SCHEMBL5923592 | 0.82 | SIGMAR1 (0.56) | SIGMAR1NCEH1LMNAGAA | |
| SCHEMBL6003215 | 0.81 | SIGMAR1 (0.54) | SIGMAR1NCEH1LMNAALDH1A1 | |
| SCHEMBL3626830 | 0.80 | SIGMAR1 (0.67) | SIGMAR1TSHRALDH1A1GAA | |
| SCHEMBL29666490 | 0.80 | SIGMAR1 (0.67) | SIGMAR1GAA | |
| SCHEMBL1614544 | 0.80 | SIGMAR1 (0.67) | SIGMAR1GAA | |
| SCHEMBL28851168 | 0.79 | SIGMAR1 (0.61) | SIGMAR1NCEH1ALDH1A1PGRGAA | |
| SCHEMBL27532540 | 0.79 | GAA (0.44) | SIGMAR1NCEH1LMNAALDH1A1PGR | |
| SCHEMBL1839015 | 0.79 | SIGMAR1 (0.65) | SIGMAR1NCEH1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103429664-B | Photocurable film-forming composition and method for producing cured film | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2016-05-11 | — | — | CN | disclosed |
| CN-102459415-B | Triazine ring-containing polymer and film-forming composition containing same | NISSAN CHEMICAL IND LTD | 2014-07-02 | — | — | CN | disclosed |
| CN-103429664-A | Photocurable film-forming composition and method for producing cured film | NISSAN CHEMICAL IND LTD | 2013-12-04 | — | — | CN | disclosed |
| CN-103270115-A | Film-forming composition | NISSAN CHEMICAL IND LTD | 2013-08-28 | — | — | CN | disclosed |
| CN-103261273-A | Triazine ring-containing polymer and film-forming composition containing the same | NISSAN CHEMICAL IND LTD | 2013-08-21 | — | — | CN | disclosed |
| CN-103168066-A | Triazine ring-containing polymer and film-forming composition containing the same | NISSAN CHEMICAL IND LTD | 2013-06-19 | — | — | CN | disclosed |
| CN-103154138-A | Film-forming composition | NISSAN CHEMICAL IND LTD | 2013-06-12 | — | — | CN | disclosed |
| US-8163753-B2 | 2-(4-(4-(4-chlorophenyl)oxazol-2-yl)phenoxymethyl)-2-methyl-6-nitro-2,3-dihydroimidazo[2,1-b]oxazole; bactericide; excellent bactericidal action against Mycobacterium tuberculosis, multi-drug-resistant Mycobacterium tuberculosis, and atypical acid-fast bacteria | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-04-24 | — | — | US | disclosed |
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |
| US-20080119478-A1 | 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis | OTSUKA PHAMACEUTICAL CO., LTD. (JP) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119478-A1 | 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis | NR2C2, NR0B2, NR4A2 | SIGMAR1 161/4885NCEH1 2204/4885LMNA 4594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.